张明磊, 李永超, 徐岷田, 郭瑞清. 赣榆县1995-2001年肾综合征出血热监测[J]. 疾病监测, 2003, 18(3): 83-87. DOI: 10.3784/j.issn.1003-9961.2003.3.83
引用本文: 张明磊, 李永超, 徐岷田, 郭瑞清. 赣榆县1995-2001年肾综合征出血热监测[J]. 疾病监测, 2003, 18(3): 83-87. DOI: 10.3784/j.issn.1003-9961.2003.3.83
ZHANG Minglei. et al, . Surveillance of Hemorrhagic Fever with Renal Syndrome in Ganyu County 1995-2001[J]. Disease Surveillance, 2003, 18(3): 83-87. DOI: 10.3784/j.issn.1003-9961.2003.3.83
Citation: ZHANG Minglei. et al, . Surveillance of Hemorrhagic Fever with Renal Syndrome in Ganyu County 1995-2001[J]. Disease Surveillance, 2003, 18(3): 83-87. DOI: 10.3784/j.issn.1003-9961.2003.3.83

赣榆县1995-2001年肾综合征出血热监测

Surveillance of Hemorrhagic Fever with Renal Syndrome in Ganyu County 1995-2001

  • 摘要: 本文分析了 1995~ 2001年肾综合征出血热 (HFRS)人间与兽间疫情及控制效果监测结果 ,7年来共发生HFRS 755例 ,年平均发病率 10.55/10万 ,死亡 8例 ,病死率 1.06% ;全年各月均有发病 ,呈现春峰和秋冬峰 ,春峰有下降趋势 ;该县 29个乡镇均有发病 ,并呈现丘陵 >平原 >沿海的地区发病特点 ;发病年龄集中在 30~ 50岁年龄组 ,占 68 .48% ;男女性别比 2.18∶1,有下降趋势 ;职业发病中以农民为主占 85.83 % ,其次学生占 7.55 % ;7年健康人群免疫水平调查显示抗 -HFRSVIgG平均阳性率 11.37% ;从临床诊断病人的血清学核实情况看 ,符合率 66.00% ,存有大量误诊。1995年以来 ,每年对春季室内、冬季野外进行宿主动物密度及带毒情况调查 ,捕获的宿主动物种类有 2目 3科 5属 6种 ,其中褐家鼠、黑线姬鼠分别为室内及野外的优势鼠种 ,带病毒率分别为 2.99%、3.28% ;春、秋季鼠带毒指数分别为 4.35、2.28,且有秋季鼠带毒指数与年发病率呈正相关。该县对一个高发乡镇 5000人接种HFRS Ⅱ 型疫苗,3年保护率达100%,并于1999年实施以疫苗接种为主导的综合防病措施,大力推广HFRS双价疫苗的接种,提高了人群的免疫水平,并降低了近两年的发病率,因此,疫苗接种是控制HFRS的有效途径。

     

    Abstract: This article showed the analysis of surveillance results of controlling hemorrhagic fever with renal syndrome (HFRS) and the epidemic of HFRS from rats and crowd during 1995-2001. There had been 755 patients of HFRS during the past seven years, the average incidence rate was 10.55/100 thousand yearly; and 8 patients had been died, the fatality of HFRS was 1.06%. The seasonal distribution: there were cases in every month all year round, which showed two peaks: spring peak (from March to June) and autumn peak (from October to January of next year).Cases of HFRS were distribtued in every towns,the characteristic:more cases in the hilly land than in the plain area,and more cases in the plain area than in the coastal area.Of all patients,68.48% was mainly in 30 to 50 age group,the ratio of sex (male:female) was 2.18:1,which showed the declined trend(r=-0.81,p<0.05).85.83% of all patients are peasants,and 7.55% of them the students.The investigation of immunized level of crowd showed that the average positive proportion of anti-HFRS IgG was 11.37%,the coincidence rate in the clinical diagnoses compared with the result of serum test was 66.00%.We carried out the investigation of inhabited rat density and their carrying virus state at home in spring and in field in autumn each year.The captured inhabited rats was divided into six species in three families of two orders.Among them,the superiority of the rat at home are R.rattus of which the carrying virus was 2.99%,and in the field the A.arariue of which carrying virus rate was 3.28%,the index of carrying virus was 4.35 in spring and 2.28 in autumn,which showed the positive correlation in comparison with the incidence rate yearly(r=0.82,P<0.05).The HFRS Ⅱ vaccine had been used on 5000 persons from the towns with the high incidence rate,and three-year protective rate was 100%.We had adopted the general protective measurements of which the vaccine inoculating was main way to control HFES.We had been advocating to inoculate vaccine in Canyu county widely,which had boosted the immunized level of crowd and declined the incidence rates of HFRS for two years.So we believed that inoculating of the HFRS vaccine was the best way of controlling HFRS.

     

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