Abstract: Objective　To analyze the surveillance results of tuberculosis (TB) in Wenzhou, Zhejiang province during 2002-2006 and evaluate the current prevention and control strategies. Methods Tuberculosis surveillance reports from 2002 to 2006 in Wenzhou were collected and analyzed. Results During this period, the active pulmonary TB registration rate and the smear-positive registration rate in local population were 28.48/lakh and 11.53/lakh respectively, and 29.42/lakh and 15.03/lakh in floating population. The new registration rate of active pulmonary TB and new smear-positive rate were 49.91/ lakh and 19.00/lakh in local population, and 50.69/lakh and 24.37/lakh in floating population. Both indicators were higher in floating population than in local population. The cohort analysis of the outcome within 1 year indicated that the average cure rate was 86.60% in local population and 84.78% in floating population. Conclusion　It is important to improve the discovery of smear-positive TB patients and the control of tuberculosis in floating population in Wenzhou.