张晓嫒, 叶长芸, 徐建国. 肠出血性大肠埃希菌O157 ∶ H7质粒 pO157 上毒力因子的研究进展[J]. 疾病监测, 2011, 26(6): 479-483. DOI: 10.3784/j.issn.1003-9961.2011.06.017
引用本文: 张晓嫒, 叶长芸, 徐建国. 肠出血性大肠埃希菌O157 ∶ H7质粒 pO157 上毒力因子的研究进展[J]. 疾病监测, 2011, 26(6): 479-483. DOI: 10.3784/j.issn.1003-9961.2011.06.017
ZHANG Xiao-ai, YE Chang-yun, XU Jian-guo. Progress on research of virulence factors on plasmid pO157 of EHEC O157 ∶ H7[J]. Disease Surveillance, 2011, 26(6): 479-483. DOI: 10.3784/j.issn.1003-9961.2011.06.017
Citation: ZHANG Xiao-ai, YE Chang-yun, XU Jian-guo. Progress on research of virulence factors on plasmid pO157 of EHEC O157 ∶ H7[J]. Disease Surveillance, 2011, 26(6): 479-483. DOI: 10.3784/j.issn.1003-9961.2011.06.017

肠出血性大肠埃希菌O157 ∶ H7质粒 pO157 上毒力因子的研究进展

Progress on research of virulence factors on plasmid pO157 of EHEC O157 ∶ H7

  • 摘要: 肠出血性大肠埃希菌O157 ∶ H7是一种重要的致病菌,可以引起不同程度人类疾病。目前已知的O157 ∶ H7的致病因子有3个,志贺毒素、粘附抹平效应毒力岛和特异性质粒pO157。其中pO157在致病过程中的作用并不十分清楚。本文结合近年来的研究进展,介绍了pO157上与细菌致病性有关的毒力因子。

     

    Abstract: Enterohemorrhagic Escherichia coli (EHEC) O157 ∶ H7 is a major pathogen, which can cause severe disease in humans. Three major virulence factors of E.coli O157 ∶ H7 have been identified including Shiga toxin, products of the pathogenicity island called locus of enterocyte effacement and products of F-like plasmid pO157. Among these virulence factors, the role of pO157 is less understood. This paper summarizes the research progress on virulence factor on pO157 of E.coli O157 ∶ H7.

     

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