全国结核病流行病学抽样调查及各省耐药监测中耐药结核病疫情资料分析
Drug resistant tuberculosis in China——a analysis on results of national tuberculosis epidemiological sampling surveys and drug resistance surveillanc
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摘要: 目的 对我国耐药肺结核的流行现状展开分析,为制定相关政策提供科学依据。 方法 分析1990、2000 和2010年三次全国结核病流行病学抽样调查资料(未包括香港、澳门和台湾地区,以下同)中不同药物的初始耐药率以及获得性耐药率的变化趋势,比较全国12个省耐药率及耐多药率的差异。 结果 根据目前我国1990、2000、2010年三次结核病流行病学抽样调查结果显示, 异烟肼和链霉素的初始耐药率呈现上升趋势(PPPP结论 为了遏制耐多药肺结核,需要尽快提高耐多药肺结核规范化治疗管理的覆盖率,通过规范化治疗来治愈耐多药肺结核患者,以控制耐多药肺结核的传染源从而降低疫情。在开展耐多药肺结核控制的同时,不可降低普通肺结核治疗管理的质量。Abstract: Objective To understand the prevalence of drug resistant tuberculosis(TB) in China and provide scientific evidence for the development of TB prevention and control strategy.Methods The analysis was conducted on the data of three national TB epidemiological surveys conducted in the mainland of China in 1990,2000 and 2010 to learn about the change trend of initial drug resistance and acquired drug resistance to different anti TB drugs and compare the differences in drug resistant rate and multidrug resistant(MDR) rate in 12 provinces.Results The analysis indicated that the initial resistance to isoniazid and streptomycin showed an upward trend(PPPPConclusion It is necessary to increase the coverage of standardized treatment and management MDR TB to stop the spread of MDR TB. Meanwhile the treatment and management of non drug resistant TB should not be neglected.
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