Objective To analyze the successful rate of the first dose live attenuated measles vaccine immunization among infants in Yuhang district and provide reference to control the high incidence of measles. Methods During June-August, 2008, 77 infants aged 8 months were selected to have measles antibody test under the permission in 3 vaccination clinics in Linping, Tangqi and Pingyao, the first blood sample was taken before the vaccination and the second one was taken 30 days after vaccination to detect the antibody titer. Fifty seven infants met the requirement for the survey. Results Among 57 infants, 4 were measles antibody-positive before vaccination (7.02%); One month after the vaccination, the positive seroconversion rate was 100%. The differences on average antibody titer between Linping and Pingyao, and between Tangqi and Pingyao had statistical significance, which indicated that the antibody titers in Linping and Tangqi were higher than that in Pingyao. Conclusion The measles vaccination in Yuhang was effective with high positive seroconversion rate. The vaccination of the children who were antibody positive before the vaccination could increase the antibody titer, which would benefit the childrens health in Yuhang. The quality of measles vaccination varied by areas, it is necessary to strengthen the training of vaccinators to increase the quality of vaccination.