Relationship between dyslipidemia and diabetes mellitus in adults in Tianjin

ObjectiveTo investigate the relationship between dyslipidemia and diabetes mellitus in adults in Tianjin.

MethodsA total of 4 479 local adults aged ≥18 years selected through multi-stratified clustering sampling in Tianjin were surveyed with a questionnaire. Multifactor Logistic regression model was used to analyze the relationship between dyslipidemia and diabetes mellitus.

ResultsThe overall prevalence rates of dyslipidemia and diabetes mellitus in the adults were 30.65% and 13.31%, respectively. The overall prevalence rates of borderline high total cholesterol (TC), borderline high triglyceridemia (TG) and borderline high LDL-C were 22.73%, 12.75% and 18.91%. The overall prevalence rates of hypercholesterolemia, hypertriglyceridemia and low HDL-C lipidemia were 7.08%, 14.18% and 15.61%, respectively. The correlation analysis indicated that fasting blood glucose level had positive correlations with TC, TG and LDL-C levels (r=0.210, P<0.001; r=0.353, P<0.001; r=0.109, P<0.001), but negative correlation with HDL-C level (r=−0.069, P<0.001). Dyslipidemia was an independent risk factor of diabetes mellitus in the adults, the odds ratio was 2.28 (95% CI: 1.89–2.75). Hypercholesterolemia, hypertriglyceridemia and low HDL-C lipidemia were independent risk factors of diabetes mellitus in the adults, the odds ratios were 1.68 (95% CI: 1.25–2.26), 2.88 (95% CI: 2.32–3.58) and 1.38 (95% CI: 1.10–1.75), respectively. Borderline high TC and borderline high TG were independent risk factors of diabetes mellitus in the adults, the odds ratios were 1.27 (95% CI: 1.03–1.57) and 1.66 (95% CI: 1.28–2.15), respectively.

ConclusionDyslipidemia is closely associated with diabetes mellitus in adults in Tianjin. The risk for diabetes mellitus increases gradually with the increase of blood lipid level. Comprehensive prevention and control of dyslipidemia and diabetes mellitus should be carried out.