Screening and treatment inclusion of multidrug resistant tuberculosis patients in Shaanxi,2015–2019

ObjectiveTo understand the detection and treatment inclusion of multidrug resistant tuberculosis (MDR TB) patients in Shaanxi province, and explore the MDR TB prevention and treatment strategies.

MethodsDrug resistance information registered in Shaanxi from 2015 to 2019 were collected from the tuberculosis management information system of Chinese Center for Disease Control and Prevention. Descriptive epidemiological methods were used for the analysis. Enumeration data were expressed by case number, rate or constituent ratio. The intergroup rate was compared by χ² test, and P<0.05 was considered to be statistically significant.

ResultsIn Shaanxi, the screening rate of MDR TB patients was 52.99%, the screening rate of multidrug resistance in new etiologic positive patients was 51.57%, and the screening rate of multidrug resistance in population at high risk was 62.25%. All the three rates began to show increasing trends year by year in 2017 (trend χ²=4 462.291, P<0.001, trend χ²=4 288.520, P<0.001, trend χ²=297.085, P<0.001). The detection rate of MDR TB patients was 8.39%. The multidrug resistance detection rate was highest in patients with TB recurrence (22.96%). The treatment inclusion rate of MDR TB patients was 72.73%. The total treatment inclusion rate of MDR TB patients and the treatment inclusion rate of new etiologic positive patients showed downward trends year by year（trend χ²＝8.788, P＝0.003; trend χ²＝12.806, P＜0.001）.

ConclusionThe screening rate, detection rate and treatment inclusion rate of MDR TB patients were not high in Shaanxi. It is necessary to further improve the prevention, control and treatment of MDR TB.