Drug resistance and molecular types of Salmonella Enteritidis in Wuxi, Jiangsu, 2012–2018

  Objective   To investigate the antibiotic resistance and pulsed field gel-electrophoresis (PFGE) patterns of Salmonella Enteritidis strains detected in Wuxi, Jiangsu province, from 2012 to 2018.

  Methods   A total of 110 strains of S. Enteritidis were isolated from diarrhea patients in outpatient departments of food-borne disease surveillance sentinel hospital, people receiving health examinations, food poisoning cases and environmental water samples in Wuxi from 2012 to 2018. Based on BD Phoenix automatic bacterial identification/susceptibility system test program and PulseNet China network laboratory standard method, we analyzed the drug susceptibilities and PFGE patterns of the 110 strains.

  Results   The 110 strains of S. Enteritidis were sensitive to ciprofloxacin, ertapenem, imipenem, meropenem, azithromycin and ceftazidime/avibactam, but showed high resistance to nalidixic acid, ampicillin and ampicillin/sulbactam. Multidrug resistances were observed in 77 strains (70.00%), and the majority of them were resistant to 3 kinds of antibiotics (45.45%, 50/110). The 110 strains were divided into 39 PFGE patterns by Xba Ⅰ. Each pattern contained 1–31 strains. EN17, EN21 and EN24 were the main PFGE patterns.

  Conclusion   S. Enteritidis strains isolated in Wuxi showed serious drug resistances, and close attention should be paid to its multidrug resistance. The PFGE patterns of the strains showed diversity and predominant patterns existed.