Analysis on hepatitis C diagnosis and reporting quality in 4 hospitals in Liangzhou district of Wuwei, Gansu, 2021−2022

  Objective  To understand the reporting quality of hepatitis C in medical institutions in Liangzhou district of Wuwei, Gansu province, and provide evidence for improving the reporting quality of hepatitis C in medical institutions.

  Methods  Hospital A, B, C and D at different levels in Liangzhou, with a large number of hepatitis C reporting and outpatient visits were selected for the survey. The verifications of confirmed hepatitis C cases and positive cases of hepatitis C virus reported by the 4 hospitals from June 1, 2021 to May 31, 2022 were conducted. Twenty hepatitis C reporting cards were randomly selected in each hospital for comparison with the reported data through internet. Software Excel 2010 and SPSS 19.0 were used to analyze and compare the case reporting rate, underreporting rate, timely reporting rate, reporting card completion rate, reporting card accuracy rate and reporting card consistency rate.

  Results  The detection rate of HCV RNA in anti-HCV positive patients in hospital B (70.29%) was significantly higher than those in other three hospitals ( χ²=30.700, P<0.010). The positive rates of HCV RNA detection in hospital A and B were higher than those in hospital C and D ( χ²=24.300, P<0.010). A total of 349 confirmed cases of hepatitis C were verified, and the overall misreporting rate of confirmed cases was 45.84%. The misreporting rate of hepatitis C was 43.12% in grade Ⅲ hospitals and 75.86% in grade Ⅱ hospitals, the difference was significant (χ²=8.200, P<0.010). Among the 213 HCV nucleic acid positive cases detected by the hospital laboratories, 109 were reported to the information system, the underreporting rate was 48.83%. The underreporting rate was 50.24% in grade Ⅲ hospitals and 12.50% in grade Ⅱ hospitals, the difference was significant (χ²=4.500, P<0.050). The reporting quality verification showed that the overall reporting timeliness rate was 86.25%, the timeliness rate s was 92.50% in grade Ⅲ hospitals, and 80.00% in grade Ⅱ hospitals, the difference was not significant (χ²=2.600, P<0.050). The overall accuracy rate of the reporting card was 80.00%, the accuracy rate was 92.50% in grade Ⅲ hospitals, and 67.50% in grade Ⅱ hospitals, the difference was significant (χ²=7.800, P<0.010).

  Conclusion  The false positive rate of hepatitis C reporting in grade Ⅱ hospitals was higher than that in grade Ⅲ hospitals in Liangzhou. The false negative rate in grade Ⅲ hospitals was higher than that in grade Ⅱ hospitals. The accuracy of reporting card in grade Ⅲ hospitals was better than that in grade Ⅱ hospitals. The training of hepatitis C diagnostic criteria in medical institutions should be strengthened to improve the laboratory detection ability and reduce the false positive and false negative reporting rate of hepatitis C.