Analysis on syphilis infection among 6366 pregnant women and their infants in Zhoushan archipelago

Objective To analyze the syphilis infection status in pregnant women and their infants in Zhoushan, provide scientific evidence for blocking vertical transmission of syphilis. Methods The test Results of 6366 pregnant women who gave birth in our hospital from 2008 to 2009, the outcomes and follow-up data of the infants were analyzed retrospectively. Results Forty six of 6366 pregnant women were positive for syphilis (0.72%). All of them were infected with latent syphilis. The 46 pregnant women were regarded as infection group, the remaining were as control group. Pregnancy syphilis was the major reason to choose cesarean section among these pregnant women, the difference was significant between infection group and control group (P0.05). The infection rate was low in the infants whose mothers received treatment during pregnancy (P0.05). The preventive treatment was conducted for the infants of syphilis infected women, so the follow up Results indicated they were all negative for syphilis. Conclusion Congenital syphilis can be well controlled by strengthening pre-marriage examination and the health care before pregnancy as well as the surveillance and standard treatment of syphilis in pregnancy.