Abstract:
Objective To understand the pathogen spectrum and epidemiological characteristics of ARI of acute respiratory infection (ARI) in Tianshui, Gansu province, from 2023 to 2024.
Methods Clinical samples were collected from 1704 ARI patients in a sentinel hospital in Tianshui during 2023-2024. Twenty-one common respiratory pathogens were detected by using multiplex real-time PCR. Software Excel 16.61 and SPSS 25.0 were used for the statistical analysis on detection results.
Results : In the 1704 patients, the overall positive rate pathogen detectionwas 58.04%. The positive rate was highest in winter (67.23%). Adolescents aged 6-17 years were the most susceptible population for ARI infection. The positive rate of Haemophilus influenzae was highest (24.82%, 423/1704). A total of 409 cases were infecteds with two or more pathogens. The differences in in Klebsiella pneumoniae and parainfluenza virus infection rates were significant between men and women (P<0.05). The difference in pathogen detection rate was significant between inpatients and outpatients (P<0.05).
Conclusion The detection of ARI pathogen showed significant age and season specific differences, different pathogens spread alternatively and co-infections were frequent. The bacterial pathogen detection rate (50.76%) was higher than viral pathogen detection rate (35.45%). The pathogen detection positive rate was higher in outpatients (67.49%) than in inpatients (32.51%), while the inpatients had higher co-infection rate. It is suggested to strengthen the surveillance for acute respiratory pathogens and take targeted prevention and control measures.
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