Abstract: Infectious disease surveillance system is important for infectious disease management. Because of the dynamic data is complex with large base, it is necessary to establish an intelligent infectious disease surveillance system to reduce the rate of underreporting of infectious diseases in China. In this study new information technology was used to analyze the infectious disease surveillance system based on closed-loop management, i.e. "information system - reporting doctor -public health department - information system" to provide evidence for the improvement of the efficiency and quality of infectious disease reporting. The system, composed of modules of early warning, intervention, reporting, docking with disease control and prevention center, and reporting, was put into use after trial operation in November 2022. It has the functions of automatic early warning, report reminding, report verifying, communication, inquiry statistics, and data analysis. . The analysis results showed that the total underreporting rate of the infectious disease decreased from 12.82% before the trial operation to 8.78% from April 2023 to December 2024, a decrease of 31.50%, and the annual average underreporting rate in 2024 decreased by 1.60% compared with previous year. It has been proved that the infectious disease surveillance system based on the closed-loop management mechanism has the characteristics of high timeliness, high accuracy and low error rate, which can improve the automation and informatization level of infectious disease reporting for the intelligent and refined management of infectious disease reporting.