Abstract:
Objective To investigate the willingness to accept prophylactic treatment in HIV/AIDS patients with latent Mycobacterium tuberculosis infection and influencing factors in Jinhua, Zhejiang province, and provide evidence for policy-making to promote prophylactic treatment in HIV/AIDS patients with latent M. tuberculosis infection.
Methods The HIV/AIDS patients visiting the designated hospitals in Jinhua from January 2024 to May 2025 were selected for the screening of latent M. tuberculosis infection. A survey on the willingness to accept prophylactic treatment was conducted in those with latent M. tuberculosis infection. In the survey, the information about their demographic characteristics, lifestyles, health status were collected, and univariate and multivariate analyses were used to identify the factors influencing their willingness to receive prophylactic treatment.
Results A total of 207 latent M. tuberculosis infection cases were detected in 1 598 HIV/AIDS patients, in whom 40.58% (84/207) were willing to have prophylactic treatment. Educational level（χ2＝10.162, P＝0.006）, medical insurance（χ2＝13.688, P＜0.001）, household income（χ2＝11.756, P＝0.003）, transmission route of HIV（χ2＝7.647, P＝0.006）, the awareness of core tuberculosis (TB) related knowledge（χ2＝18.424, P＜0.001）, and health education by medical staff（χ2＝7.752, P＝0.005）were significantly associated with the willingness to accept prophylactic treatment. Patients with medical insurance, better awareness of core TB related knowledge, and adequate health education from medical staff showed higher willingness to accept prophylactic treatment.
Conclusion The willingness to accept prophylactic treatment in HIV/AIDS patients with latent M. tuberculosis infection in Jinhua was influenced by medical insurance coverage, awareness of core TB related knowledge and health education from medical staff. It is necessary to strengthen financial support, training of medical personnel, and health education about TB prevention and control knowledge.
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