Abstract: Dengue fever and Chikungunya fever are diseases mainly transmitted by Aedes aegypti and Aedes albopictus. Characterized by rapid transmission, extensive affected area and great difficulty in prevention and control, they are key imported infectious diseases for the prevention and management in the mainland of China, as well as major communicable diseases requiring priority response in the world. The transmission is closely associated with the density of Aedes. Up to now, Chikungunya fever cases have been reported in 119 countries and regions in the world, and dengue fever is endemic in over 100 tropical and subtropical countries. A total of 14.6 million dengue fever cases were reported globally in 2024, showing a rapid increase compared with 2000. As representative tropical and subtropical regions, Singapore and Hong Kong, China have long been affected by the two mosquito-borne diseases mentioned above, and they have developed mature strategies and obtained practical experience in the precise control of Aedes density. From five aspects of governance model, legal guarantee, technological application, community mobilization and environmental management, this paper systematically summarizes and compares the practical paths of Aedes density control in Singapore and China’s Hong Kong, extracts replicable and promotable core prevention and control experience, analyzes the adaptability of such experience in combination with the domestic foundation of mosquito control and local epidemiological characteristics of China, to provide scientific evidence for China to improve vector control against dengue fever, Chikungunya fever and other similar mosquito-borne diseases, and lower the risks of importation and indigenous transmission of the diseases.