2018-2023年甘肃省肺结核患者延迟就诊状况分析

Analysis on medical care seeking delay in pulmonary tuberculosis patients in Gansu, 2018−2023

  • 摘要:
    目的 为深入了解甘肃省肺结核患者就诊延迟的现状及其关键影响因素,从而为全省肺结核患者的早期发现和防控策略提供科学支持。
    方法 采用描述性统计方法,整合2018-2023年中国疾病预防控制信息管理系统内甘肃省肺结核患者的数据,对患者就诊延迟情况进行空间分布的可视化研究;并基于患者的性别、年龄、民族、职业、来源及治疗类型等变量,运用回归模型分析就诊延迟的关键影响因素,结果进行统计学分析。
    结果  2018-2023年甘肃省登记管理肺结核患者为38088例,患者就诊中位天数为27(7~60)d,延迟就诊患者24520例,延迟就诊率为64.37%(24520/38088)。 空间分布显示,延迟就诊率高的区域主要集中在甘肃省的中部、东部和南部的县(区)。 不同性别、民族、职业、人员流动与否、年龄段、不同病原学检查结果、有无合并症、主动发现和被动发现患者之间在延迟就诊和非延迟就诊中的比例,差异有统计学意义(均P<0.001)。 与其他民族相比,汉族患者发生就诊延迟的风险更高比值比(OR)=1.18,95%置信区间(CI):1.10~1.27;与学生患者相比,农牧民患者发生就诊延迟的风险更高(OR=1.16,95%CI:1.01~1.34);与非流动患者相比,流动人口患者发生就诊延迟的风险更高(OR=1.11,95%CI:1.02~1.19);与病原学阳性患者相比,病原学阴性患者发生就诊延迟的风险更高(OR=1.06,95%CI:1.01~1.10;与有合并症患者相比,无合并症患者发生就诊延迟的风险更高(OR=1.21,95%CI:1.11~1.32);与主动发现患者相比,被动发现患者发生就诊延迟的风险更高(OR=6.04,95%CI:5.69~6.41)。
    结论  在2018-2023年的6年期间,甘肃省登记管理的肺结核患者延迟就诊情况依然严峻。 汉族群体、从事农牧业的人口、流动人口、病原学检测结果为阴性的个体、无并发症的患者以及被动发现的病例,均是导致延迟就诊的关键因素。 应着重加强对农牧民和流动人口等群体的健康教育工作,并加强患者的主动发现机制,以优化防控策略。

     

    Abstract:
    Objective  To understand the current status of medical care seeking delay and key influencing factors in pulmonary tuberculosis (TB) patients in Gansu province, and provide scientific support for the early detection and prevention of pulmonary TB in Gansu.
    Methods  Descriptive statistical method was used to analyze registered data of pulmonary TB patients in Gansu during 2018 - 2023 collected from China Disease Prevention and Control Information Management System. Spatial distribution visualization was conducted to analyze the medical care seeking delay in the pulmonary TB patients. Based on variables such as gender, age, ethnicity, occupation, patient origin, and treatment type, regression models were used to analyze key factors influencing the medical care seeking delay. Statistical significance was set at P<0.05.
    Results  From 2018 to 2023,a total of 38 088 pulmonary TB patients were registered in Gansu. The median interval between onset and medical care seeking was 27 (7-60) days, and 24 520 patients had medical care seeking delay (64.37%).Regions with high seeking delay rates were in central, eastern and southern Gansu. Significant differences were observed in the proportions of delayed and non-delayed treatment among the patients in different gender, ethnic, occupation, residence and age groups, or with different pathogen test results, with complications or not, and detected by different methods (all P<0.001).Compared with other ethnic groups, the patients in Han ethnic group had higher risk for medical care seeking delay odd ratio (OR)=1.18, 95% confidential interval(CI):1.10-1.27. Compared with students, farmers and herders had higher risk for medical care seeking delay (OR=1.16, 95%CI:1.01-1.34). Compared with non-floating population, floating population had higher risk for medical care seeking delay (OR=1.11,95%CI:1.02-1.19). Compared with pathogen-positive patients, pathogen-negative patients had higher risk for medical care seeking delay (OR=1.06, 95%CI: 1.01-1.10). Compared with the patients with complications, those without complications had higher risk for medical care seeking delay (OR=1.21, 95%CI:1.11-1.32). Compared with the actively detected cases, the passively detected cases had higher risk for medical care seeking delay (OR=6.04, 95%CI: 5.69-6.41).
    Conclusion From 2018 to 2023, the prevalence of medical care seeking delay in pulmonary TB patients was high in Gansu. Key factors contributing to medical care seeking delay included Han Chinese ethnicity, being farmer or herder, being floating, being pathogen-negative, having no complication, being passively detected case. In the future, it is necessary to strengthen the health education in farmers, herders, and floating population, and improve active case detection to optimize the prevention and control strategies for pulmonary TB.

     

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