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李德好, 胡绪敬, 徐丽, 程晋, 胡乐华, 谭绪健. 脑膜炎奈瑟氏菌对常用抗菌药物敏感性监测[J]. 疾病监测, 1996, 11(11): 405-407.
DOI:
10.3784/j.issn.1003-9961.1996.11.405
Citation: Li Dehao et al, Surveillance on Antibiotic Sensitivity of <i>Neisseria meningitidis</i>[J]. Disease Surveillance, 1996, 11(11): 405-407. DOI: 10.3784/j.issn.1003-9961.1996.11.405
Citation: Li Dehao et al, Surveillance on Antibiotic Sensitivity of <i>Neisseria meningitidis</i>[J]. Disease Surveillance, 1996, 11(11): 405-407. DOI: 10.3784/j.issn.1003-9961.1996.11.405
脑膜炎奈瑟氏菌对常用抗菌药物敏感性监测
摘要:
本文就1966～1993年21个省市分离的218株A、B和C群脑膜炎奈瑟氏菌(Nm)对7种常用抗菌药物的敏感性进行了监测。在108株A群Nm中20株(18.5％)对SMZ耐药，其中17.3％的病人菌株，21.2％的带菌者菌株耐药；31株(28.7％)对ASP耐药。在101株B群Nm中40株(39.6％对SMZ耐药，其中43.3％的病人菌株和34.1％的带菌者菌株耐药，17株(16.8％)对ASP，10株(9.9％)对cF耐药。在9株c群Nm巾5株对SMZ，2株对ASP耐药。未发现Nm对Chl耐药。实验结果提示我们今后在流脑治疗和化学预防上应加强Nm对抗菌药物敏感性的监测，这有助于提高这些药物对流脑防治的效果。
English
Surveillance on Antibiotic Sensitivity of <i>Neisseria meningitidis</i>
Abstract:
218 strains of Neisseria meningitidis(Nm)serogroup A，B and C were collected from 21 provinces of China in 1966～1993．their sensitivity to 7 routine antibiotics were determined by us-ing the method of improved Kirby-Bauer and agar dilution．On 108 strains of serogroup A Nmtested．20 strains were discovered to be resistant to SNZ，(of which 13 strains were isolated from patients and 7 stains frombaeterium carriers)．31 strains resisted ASP．In 101 strains of serogroup B Nm．40 straino resisted SNZsupr/sup．(of which 26 strains isolated from patients and 14 straino from bacterium carriers);17 strains resisted ASP and 10 strains resisted CF．In 9 strains of serogroup CNm．5 strains resisted SMZsupr/sup；2 strains resisted ASP．We did not discovered the risistant Chl straim 0f Nm．The resu[ts showed that we should strengthen the surveillance on the antibiotic sensitivity 0f Nm in the control of epidemic meningitis．
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