Abstract: Major infectious diseases in Hubei were hemorrhagic fever, flu, epidemic cerebrospinal meningitis, typhoid, dysentery, hepatitis A and etc During the flood period, some strategies such as:complete enviromental cleaning, drinking water and food hygiene management, vaccination and case reporting were strengthened. So, after flood theseinfectiousdiseases were limited in a small region thus to win thecompletevictory of no serious epidemic following the flood".