目的调查病毒性脑膜炎的流行状况 ,进行病原学检测。方法对流行地区 38例儿童病毒性脑膜炎发病情况作个案调查 ,并对患儿的脑脊液和粪便进行病原学检测。结果共收集的 2 4份脑脊液标本、32份粪便标本进行病毒分离。在 2份脑脊液标本中分离出埃可 30病毒、柯萨奇B5 ;11份粪便标本中分离出埃可 30病毒、柯萨奇B5、柯萨奇B3。从 38例患儿脑脊液和粪便中分离出 3型肠道病毒 ,脑脊液中病毒分离出阳性率 8.3% (2/24 ) ,粪便中病毒分离阳性率 34.4 % (11/32 )。其中埃可 30病毒在脑脊液分离率为 4.2 % (1/24 ) ;在粪便中的分离率为 28.1% (9/32 )。结论本次流行的病原可能以埃可 30病毒为主 ,也可能存在合并柯萨奇B5病毒等 2种或以上的肠道病毒。
Objective To explore the epidemic feature and detect the pathogen of viral encephalitis. Methods 38 children suffering from viral encephalitis were investigated. The pathogenesis of cevebrospinal fluid (CSF) and stool from the patients were detected. Results The experiment on virus isolation from 24 samples of CSF and 32 samples of stool was carried out. Acho 30 and Coxsackie B were isolated from 2 samples of CSF. Acho30?Coxsackie B5 and Coxsackie B3 were isolated from 11 samples of stool. The type 3 of enterovirus was isolated from CSF and stool of 38 patients.The rate of virus isolation from CSF stool was 8.3%(2/24)、34.4%(11/32) respectively.The rate of Acho30 isolation from CSF、stool was 4.2%(1/24)、28.1%(9/32),respectively.Conclusion Acho30 was the main pathogen of epidemic viral encephalitis,and the pathogent of epidemic viral encephalitis was more than that of Enterovirus.