Study on the geographic distribution of liver cancer mortality and HbsAg carrier rate in China
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摘要: 目的 描绘中国肝癌死亡水平地理分布图(未包括香港、澳门和台湾地区)和乙肝病毒表面抗原(HBsAg)携带水平地理分布图,描述中国肝癌死亡水平和HBsAg携带水平的地理分布特征.研究肝痛死亡水平和HBsAg携带水平之间的关系.方法 使用全国疾病监测系统的死亡监测数据和全国肝炎血清学流调数据,分别绘出中国疾病监测点的肝癌死亡水平和各省HBsAg携带水平的地理图.比较两者的地理分布,并对各省肝癌死亡率和HBsAg携带率进行相关性检验.绘制监测点不同性别人群的肝癌死亡水平图,揭示不同性别人群的肝癌死亡率和HBsAg携带率的分布特点.结果 中国肝癌死亡率和HBsAg携带率均表现为男性高于女性,肝癌死亡率分布特点为东高西低即东部沿海地带为高发区,西部(西北、西南)为低发区,HBsAg携带率的高发区为东南沿海一带以及内陆的西藏和宁夏.两者的地理分布特点有相似性,统计学结果显示肝癌死亡率和HBsAg携带率存在正相关关系.结论 中国HBsAg携带率的高低和肝癌死亡率的水平存在相关关系.Abstract: Objective The present study was conducted to depict the geographic distribution of liver cancer mortality and the HBsAg carrier rate in China (Hong Kong and Macao Special Administrative Region and Taiwan Area not included) and to get insight into the relationship between liver cancer mortality and the HBsAg carrier rate. Methods The surveillance data on the mortality from the National Disease Surveillance Information Management System and the data from the national hepatitis seroepidemiologic survey were used to depict the geographic maps of liver cancer mortality in the national disease surveillance sites of and of the HBsAg carrier rate in individual provinces, with the geographic distribution of the two rates compared. The correlation between the two rates in individual provinces was tested. Liver cancer mortality by sex in the surveillance sites was depicted to reveal the characteristics of the distribution of liver cancer mortality and the HBsAg carrier rate by sex. Results The liver cancer mortality and the HBsAg carrier rate in China were both higher among males than among females. The mortality of liver cancer was high in the Western China and low in the western China, I.e a high incidence in the eastern costal belt and a low incidence in the Eastern China (northeastern and southeastern regions). The HBsAg carrier rate was high in the coastal belt in the southeastern region, Tibet and Ningxia Province. There was a similarity in the geographic distribution of the two conditions. Statistical analysis showed that there was a positive correlation between the mortality of liver cancer and the HBsAg carrier rate. Conclusion There is a correlation between the mortality of liver cancer and the HBsAg carrier rate in China.
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Key words:
- liver cancer /
- Hbsag /
- geographic distribution /
- disease surveillance
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