目的 研究太原市肾综合征出血热(HFRS)的流行因素、流行规律,为有效防制提供依据.方法 根据全国监测点监测方案进行监测,采用免疫荧光方法检测HFRS抗原、抗体,开展人间疫情、鼠间疫情监测和控制效果评价.结果 人间监测结果表明,太原市共发生HFRS病例1040例,死亡15例,病死率为1.44%.发病季节高峰呈春季单峰(3～5月),发病年龄以青壮年为主,发病性别男多于女(4.62:1),发病职业以工人最多.发病地区分布于所辖10县(区、市),城区发病大于郊县.鼠间监测结果表明,20年共捕获小兽4科6目13种.室内捕获褐家鼠和小家鼠2种,优势鼠种为褐家鼠,其带病毒率为5.88%;野外捕获鼠13种,优势鼠种为小家鼠、大仓鼠,未检出带病毒野鼠.结论 太原市为单纯家鼠型疫区,褐家鼠是本病主要宿主动物和传染源.
Objective The present study was conducted to find out the epidemiological factors and pattern of the hemorrhagic fever with renal syndrome (HFRS) in Taiyuan for the purpose of effective control of HFRS. Methods The monitoring was conducted according to the National HFRS Surveillance Program. The immune fluorescence assay was used to detect the HFRS antigen and antibody. The efficacy of the monitoring and control of the epidemic among residents and rats was then evaluated. Results 1040 cases and 15 deaths of HFRS were recorded in the surveillance in Taiyuan,with the case fatality of 1.44%. The duration for peak prevalence was singly in spring from March to May,and the highest incidence was found among the youth and the workers. The ratio of sex was 4.62∶1,male higher than female. The cases were distributed over ten counties (districts and cities) in Taiyuan,more cases being found in urban area than rural counties. The monitoring results among rats indicated that the captured rats could be divided into 13 species in 4 families of 6 orders in the last 20 years. Rattus norvegicus,which was predominant and had the virus carrier rate of 5.88%,and mus musculus were identified indoors. Among the 13 species of identified outdoor rats,cricetulus trition and house mice were predominant,and there was no HFRS virus found among them. Conclusion Taiyuan is an HFRS epidemic area where the domestic rodent was the single infective source. Rattus norregicus was the main host of HFRS virus and infective source.