目的 了解浙江省杭州市高危人群中艾滋病流行趋势及危险因素,为决策部门评估艾滋病防治工作效果及制定防治策略措施提供科学依据。方法 2006 年在杭州市分别对258 名性病门诊就诊者、262名吸毒者以及250名暗娼进行艾滋病病毒（HIV）哨点监测,应用酶联免疫吸附试验（ELISA）对样本进行HIV筛查。结果 258名性病门诊就诊者HIV阳性检出2例，阳性率为0.8%，梅毒阳性检出53例，阳性率为20.5%；79.1%的调查对象（204人）在近3个月有非婚性行为，其中仅10.3%在婚外性行为中每次都使用安全套，45.3%的调查对象患有其他性病。吸毒人群HIV阳性率为2.3%，梅毒阳性率0.4%，42.4%的吸毒者有注射毒品的行为，其中40.5%的注射吸毒者曾与他人共用过注射器或针头，7.3%的调查对象发生过商业性行为，其中36.8%在商业性行为中从不使用安全套；暗娼人群中未检出HIV抗体阳性者，梅毒阳性率为17.6%，仅52.0％的调查对象在入妇教所前1个月与客人发生性行为时每次都使用了安全套，1.2％的暗娼为吸毒者，但无静脉吸毒史。结论 监测结果表明，HIV在杭州市性病患者、吸毒者等高危人群中流行,存在HIV传播的多种危险性因素。
Objective This study was performed to determine the prevalence and risk factors of HIV in high-risk population, providing evidence for evaluating the effectiveness of HIV prevention and development of control strategies. Methods In 2006, a total of 258 STD outpatients, 262 drug abusers and 250 sex workers were screened for HIV antibody by enzyme linked immunosorbent assay(ELISA) in Hangzhou. Results The infection rates of HIV and syphilis among STD outpatients were 0.78% and 20.5%, respectively. 79.1% of subjects had extramarital sex activities the three months, but only 10.3% of them used condom each time. 45.3% of them suffered from other STDs. The infection rates of HIV and syphilis among drug abusers were 2.3% and 0.4%, respectively. 42.4% of used abusers had history of intravenous injection and 40.5% of them syringes sharing. 7.3% of these subjects used to have commercial sex activities but 36.8% of them had never used condoms during commercial sex; No HIV carrier was detected among the sex workers, whose infection rate of syphilis was 17.6%. Only 52.0％ of them used condoms each time in the past month when having sex with their clients. 1.2% of sex workers abused drugs without history of intravenous injection. Conclusion The results of this surveillance indicate that HIV is prevalent among high-risk population such as drug abusers and STD outpatients with multiple risk factors associated with HIV transmission.