伤寒与甲型副伤寒实验室诊断方法的研究进展

张力 阚飙

引用本文: 张力, 阚飙. 伤寒与甲型副伤寒实验室诊断方法的研究进展[J]. 疾病监测, 2009, 24(4): 293-297. DOI: 10.3784/j.issn.1003-9961.2009.04.023 shu
Citation:  ZHANG li and KAN Biao. Progress on laboratory diagnosis for typhoid fever and paratyphoid fever[J]. Disease Surveillance, 2009, 24(4): 293-297. DOI: 10.3784/j.issn.1003-9961.2009.04.023 shu

伤寒与甲型副伤寒实验室诊断方法的研究进展

摘要: 伤寒沙门菌和副伤寒沙门菌是引起肠热症的病因,在发展中国家是威胁人们健康的重要问题。两者临床症状难于区分,确切的病原学检测及鉴别诊断非常必要。本文回顾了伤寒从分离培养、血清学方法到PCR方法,以及鉴别伤寒和甲型副伤寒沙门菌感染的几种多重PCR方法。这几种多重PCR方法分别以扩增Irfb/I基因簇中伤寒和甲型副伤寒沙门菌各自特异基因,扩增O抗原、Vi抗原、鞭毛蛋白编码基因及扩增多个特异的蛋白编码序列达到鉴别诊断的目的。

English

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  • 收稿日期:  2008-09-03
  • 刊出日期:  2009-04-30
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