结果 伴有肥胖基础的甲型H1N1流感组患者的病程、发热时间、胸闷胸痛、肺部啰音、C-反应蛋白(C-creactive protein,CRP)水平、心肌酶谱上升例数、并发肺炎的发生率高于无肥胖基础的甲型H1N1流感组患者,差异有统计学意义(P0.05);两组间咳嗽、咽痛、流涕、头痛、胃肠道症状发生率,血常规、肝肾功能等差异均无统计学意义(P＞0.05)。
Objective To identify the clinical characteristics of obese patients with 2009 pandemic influenza A (H1NI) , providing the basis for development of clinical decision-making.
Methods The clinical data on 42 obese patients with 2009 pandemic influenza A (H1NI) (the obesity group) and 72 non-obese patients with the same infection (the non-obesity group) being hospitalized from June 2009 to March 2010 were collected and analyzed retrospectively.
Results Comparing with the non-obesity group, the obesity group demonstrated longer course of disease and duration of fever, more noticeable dyspnea, stethalgia and pulmonary rales, higher CRP (C-reactive protein) levels, more cases with abnormal myocardial enzymes, and higher incidence of combined pneumonia. The differences were significant (P0.05). The differences in the incidence of cough, sore throat, headache, and gastrointestinal symptoms, as well as the levels of routine blood tests and liver and renal functions, were insignificant between two groups (P0.05).
Conclusion The clinical manifestations of 2009 pandemic influenza A (H1NI) are more severe in obese patients than in non-obese ones.