莱姆病螺旋体的转移感染和致病机制

郝琴 万康林 徐建国

引用本文: 郝琴, 万康林, 徐建国. 莱姆病螺旋体的转移感染和致病机制[J]. 疾病监测, 2011, 26(6): 475-478. DOI: 10.3784/j.issn.1003-9961.2011.06.016 shu
Citation:  HAO Qin, WAN Kang-lin and XU Jian-guo. Mechanism of infection transmission and pathogenesis of Borrelia burgdorferi [J]. Disease Surveillance, 2011, 26(6): 475-478. DOI: 10.3784/j.issn.1003-9961.2011.06.016 shu

莱姆病螺旋体的转移感染和致病机制

    作者简介: 郝琴,女,山西省平陆市人,主要从事莱姆病的控制和科研工作;
    通信作者: 徐建国, xujianguo@icdc.cn
  • 基金项目: 国家科技重大专项(艾滋病和病毒性肝炎等重大传染病防治专项)课题(No.2008ZX10004-010;No.2009ZX10004-203)

摘要: 本文主要就莱姆病螺旋体从蜱到宿主动物的转移感染以及在宿主体内存活并致病的机制进行了的阐述,包括螺旋体在蜱内定居以及感染宿主动物过程中蛋白的变化及作用;螺旋体在宿主体内致病的各种机制(病原体本身的作用、免疫逃避、细胞因子的作用、自身免疫)。

English


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  • 通信作者:  徐建国, xujianguo@icdc.cn
  • 收稿日期:  2011-03-04
  • 刊出日期:  2011-06-25
通信作者: 陈斌, bchen63@163.com
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