霍乱弧菌对肠道中胆盐胁迫作用的反应调节

高艳 逄波 阚飙

引用本文: 高艳, 逄波, 阚飙. 霍乱弧菌对肠道中胆盐胁迫作用的反应调节[J]. 疾病监测, 2011, 26(6): 484-487. DOI: 10.3784/j.issn.1003-9961.2011.06.018 shu
Citation:  GAO Yan, PANG Bo and KAN Biao. Response and regulation of Vibrio cholerae to bile stress in intestinal tract[J]. Disease Surveillance, 2011, 26(6): 484-487. DOI: 10.3784/j.issn.1003-9961.2011.06.018 shu

霍乱弧菌对肠道中胆盐胁迫作用的反应调节

    作者简介: 高艳,女,黑龙江省集贤县人,主要从事霍乱弧菌分子生物学研究工作;
    通信作者: 阚飙, kanbiao@icdc.cn
  • 基金项目: 国家自然科学基金 (No. 30800987)

摘要: 作为肠道致病菌,霍乱弧菌必须耐受人体内的胃酸、胆盐、高渗和低氧等胁迫条件,才能在肠道定植、繁殖。胆盐由肝脏合成,在胆囊储存并分泌到肠道。其主要作用是帮助脂肪代谢,并有一定杀菌作用。本文综述了胆盐如何作用于霍乱弧菌,霍乱弧菌如何感受肠道内的胆盐刺激,并采用何种机制来耐受其杀菌作用。

English


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文章相关
  • 通信作者:  阚飙, kanbiao@icdc.cn
  • 收稿日期:  2011-03-24
  • 刊出日期:  2011-06-25
通信作者: 陈斌, bchen63@163.com
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