目的 分析浙江省诸暨市手足口病流行病学特征,为制定预防控制方案提供依据。 方法 对2008-2011年诸暨市手足口病监测资料及部分病例病原核酸检测资料进行分析。 结果 2008-2011年共报告手足口病5273例,年平均发病率为99.89/10万,4-7月为发病高峰,9-10月出现小高峰;发病人群中散居儿童占59.34%,5岁组占90.63%。聚集性疫情91起,幼托机构占94.51%;重症病例18例,死亡3例,0~2岁组占77.78%,以外地户籍儿童为主。病原学特征肠道病毒71型(EV71)感染占40.18%,柯萨奇病毒A组16型(Cox A16)感染占30.25%,其中重症病例和死亡病例以EV71感染为主;聚集性疫情以EV71和Cox A16感染为主,二者差异无统计学意义(P0.05)。 结论 诸暨市手足口病的流行有明显地区、季节、人群特征,在手足口病监测和防控工作中,应根据手足口病的流行特点,关注流行高峰和重点人群,制定科学规范的防控预案。
Objective To understand the epidemiological characteristics of hand, foot and mouth disease (HFMD) in Zhuji and provide scientific evidence for the development of prevention and control strategy. Methods The analysis on local HFMD surveillance data and etiological detection results of some HFMD cases from 2008 to 2011 were conducted. Results A total of 5273 HFMD cases, including 18 severe cases and 3 deaths, were reported during this period with the annual average incidence of 99.89/lakh, The incidence peak occurred during April-July and sub-peak occurred during September-October of a year. The cases in children outside child care settings accounted for 59.34% of the total and most cases were distributed in age group 5 years (90.63%). Totally 91 epidemics occurred in child care settings (94.51%) and other places. The severe cases and deaths mainly occurred in age group 0-2 years in floating population, accounting for 77.78%. The cases caused by EV71 accounted for 40.18% and the cases caused by Cox A16 accounted for 30.25%, but the severe cases and deaths were mainly caused by EV71. The epidemics were caused by either EV71 or Cox A16, the difference had no statistical significance (P0.05). Conclusion The area, seasonal and population distributions of HFMD cases were obvious in Zhuji. It is necessary to develop effective prevention and control strategy according to epidemiological characteristics of HFMD.