霍乱弧菌是霍乱的病原体,广泛存在于海洋及江河入海口环境中。在不良环境中霍乱弧菌会进入活的非可培养状态(viable but non-culturable state, VBNC),常规分离方法检测不到,在条件合适时VBNC状态的霍乱弧菌会复苏为可培养状态。本文对近年霍乱弧菌VBNC相关研究做了回顾,以期能够为霍乱弧菌越冬机制以及霍乱的监测提供参考。
Vibrio cholerae, widely existing in marine and estuarine environments, is the causative agent of cholera. When V. cholerae cells are subjected to stringent conditions they may form viable but not culturable (VBNC) cells. These bacteria can recover from VBNC state and may pose risk to human. This paper summarizes the progress in the research of the VBNC state of V. cholerae for the better surveillance of V. cholerae.