煤矿职业健康检查人群血清-谷氨酰转肽酶与血压、血脂、血糖相关性分析

尚红光 王爱珉 卫俊峰 陈秋生 袁晓芳

尚红光, 王爱珉, 卫俊峰, 陈秋生, 袁晓芳. 煤矿职业健康检查人群血清-谷氨酰转肽酶与血压、血脂、血糖相关性分析[J]. 疾病监测, 2016, 31(8): 663-667. doi: 10.3784/j.issn.1003-9961.2016.08.012
引用本文: 尚红光, 王爱珉, 卫俊峰, 陈秋生, 袁晓芳. 煤矿职业健康检查人群血清-谷氨酰转肽酶与血压、血脂、血糖相关性分析[J]. 疾病监测, 2016, 31(8): 663-667. doi: 10.3784/j.issn.1003-9961.2016.08.012
SHANG Hong-guang, WANG Ai-min, WEI Jun-feng, CHEN Qiu-sheng, YUAN Xiao-fang. Correlation between serum gamma-glutamyl transpeptidase and blood pressure, blood lipids and blood glucose in coal miners receiving occupational health examination[J]. Disease Surveillance, 2016, 31(8): 663-667. doi: 10.3784/j.issn.1003-9961.2016.08.012
Citation: SHANG Hong-guang, WANG Ai-min, WEI Jun-feng, CHEN Qiu-sheng, YUAN Xiao-fang. Correlation between serum gamma-glutamyl transpeptidase and blood pressure, blood lipids and blood glucose in coal miners receiving occupational health examination[J]. Disease Surveillance, 2016, 31(8): 663-667. doi: 10.3784/j.issn.1003-9961.2016.08.012

煤矿职业健康检查人群血清-谷氨酰转肽酶与血压、血脂、血糖相关性分析

doi: 10.3784/j.issn.1003-9961.2016.08.012

Correlation between serum gamma-glutamyl transpeptidase and blood pressure, blood lipids and blood glucose in coal miners receiving occupational health examination

  • 摘要: 目的 探讨肝功能指标血清-谷氨酰转肽酶(GGT)与代谢综合征(MS)的相关性。方法 选取邯郸地区2372名煤矿工人为研究对象,按血清GGT水平四分位数分为四组,以SPSS 17.0统计软件分析其血清GGT与收缩压(SBP)、舒张压(DBP)、空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、体重指数(BMI)之间的相关性。结果 血清GGT与年龄、SBP、DBP、TC、TG、HDL-C、FPG、BMI比较差异均有统计学意义(P0.001),最低四分位组到最高四分位组,随着血清GGT水平的上升,SBP、DBP、TC、TG、FPG、BMI各指标水平升高,HDL-C水平降低。通过Pearson分析,研究对象的GGT水平与年龄、TG、TC、FPG、SBP、DBP、BMI等均呈显著正相关(r值分别为0.110、0.313、0.352、0.163、0.174、0.141、0.212),与HDL-C呈负相关(P0.01)。多因素逐步回归分析后显示, TG、TC、FPG、SBP、血红蛋白(HGB)指标为该人群血清GGT危险因子(值分别为0.215、0.274、0.100、0.098、0.077)。结论 煤矿在岗工人血清GGT水平同MS组分血压、血脂、血糖呈显著相关,可为该人群MS的早期诊断提供一定的参考。
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出版历程
  • 收稿日期:  2016-01-06
  • 刊出日期:  2016-08-20

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