幽门螺杆菌根除治疗能否影响胃肠微生态平衡

陈烨

陈烨. 幽门螺杆菌根除治疗能否影响胃肠微生态平衡[J]. 疾病监测, 2018, 33(4): 282-284. doi: 10.3784/j.issn.1003-9961.2018.04.006
引用本文: 陈烨. 幽门螺杆菌根除治疗能否影响胃肠微生态平衡[J]. 疾病监测, 2018, 33(4): 282-284. doi: 10.3784/j.issn.1003-9961.2018.04.006
Chen Ye. Would Helicobacter pylori eradication influence dysbiosis of gastrointestinal microbiota[J]. Disease Surveillance, 2018, 33(4): 282-284. doi: 10.3784/j.issn.1003-9961.2018.04.006
Citation: Chen Ye. Would Helicobacter pylori eradication influence dysbiosis of gastrointestinal microbiota[J]. Disease Surveillance, 2018, 33(4): 282-284. doi: 10.3784/j.issn.1003-9961.2018.04.006

幽门螺杆菌根除治疗能否影响胃肠微生态平衡

doi: 10.3784/j.issn.1003-9961.2018.04.006
详细信息
    作者简介:

    陈烨,女,江苏省扬州市人,教授,主任医师,主要从事幽门螺杆菌及胃肠微生态失衡相关疾病的基础、转化与临床研究工作

  • 中图分类号: R537.6

Would Helicobacter pylori eradication influence dysbiosis of gastrointestinal microbiota

  • 摘要: 人体胃肠道是微生物种类最多、功能最强大的微生态系统,胃肠道微生态失衡与多种疾病的发生发展密切相关。人幽门螺杆菌(HP)是定植在胃内的一种致病菌,关于HP感染的处理,多个国际指南或国内共识意见均明确给出了主要包含质子泵抑制剂和2种抗生素的根除方案,随着对HP感染认识的加深和治疗方案的普及,HP根除是否会导致胃肠道微生态的失衡并带来失衡相关后果,这一问题日益受到关注。本文将围绕这一问题进行文献综述并提出自己的认识。
  • [1] Malfertheiner P,Megraud F,O' Morain CA,et al.Management of Helicobacter pylori infection-the Maastricht V/Florence consensus report[J].Gut,2016,66(1):6-30.DOI: 10.1136/gutjnl-2016-312288.
    [2] Dicksved J, Lindberg M, Rosenquist M, et al.Molecular characterization of the stomach microbiota in patients with gastric cancer and in controls[J].J Med Microbiol,2009,58(Pt 4):509-516.DOI: 10.1099/jmm.0.007302-0.
    [3] Aviles-Jimenez F,Vazquez-Jimenez F,Medrano-Guzman R,et al.Stomach microbiota composition varies between patients with non-atrophic gastritis and patients with intestinal type of gastric cancer[J].Sci Rep,2014,4:4202.DOI: 10.1038/srep04202.
    [4] Jakobsson HE,Jernberg C,Andersson AF,et al.Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome[J].PLoS One,2010,5(3):e9836.DOI: 10.1371/journal.pone.0009836.
    [5] 中华医学会消化病学分会幽门螺杆菌和消化性溃疡学组,全国幽门螺杆菌研究协作组,刘文忠,等.第五次全国幽门螺杆菌感染处理共识报告[J].中华消化杂志,2017,37(6):364-378.

    DOI:10.3760/cma.j.issn.0254-1432.2017.06.002.Helicobacter Pylori and Peptic Ulcer Group,Gastroenterology Society of Medical Association.The 5th Report of National Consensus on H.pylori infection treatment[J].Chin J Dig, 2017,37(6):364-378.DOI:10.3760/cma.j.issn.0254-1432.2017.06.002.
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出版历程
  • 收稿日期:  2018-04-10

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