Abstract:
Objective To understand the measles antibody level in healthy population in Changping district of Beijing, discover the susceptible population and disease spread risk, and provide scientific evidence for measles elimination strategies.
Methods Blood samples were collected from 300 healthy persons selected through simple random sampling in Changping for the detection of serum IgG against measles virus with enzyme linked immunosorbent assay (ELISA).
Results The measles antibody positive rate was 82.22% in healthy population in Changping, and the geometric mean concentration (GMC) of the antibody was 1 109.59 mIU/ml. The difference in GMC was not significant between age group 1–4 years and age group 5–9 years (F=0.734, P>0.05). The differences in measles antibody positive rate and GMC between males and females and among the people with different household registration status and doses of measles vaccination had no significance. After the immunization of measles-containing vaccine (MCV), the differences in measles antibody positive rate and GMC among age groups <1 year, 1–4 years and 5–8 years were not significant.
Conclusion The positive rate of measles antibody was at high level in healthy population in Changping, but it is still necessary to strengthen the MCV immunization in adults and other age groups at risk, especially in college students.