反向病原学

徐建国

徐建国. 反向病原学[J]. 疾病监测, 2019, 34(7): 593-598. doi: 10.3784/j.issn.1003-9961.2019.07.005
引用本文: 徐建国. 反向病原学[J]. 疾病监测, 2019, 34(7): 593-598. doi: 10.3784/j.issn.1003-9961.2019.07.005
Jianguo Xu. Reverse microbial etiology[J]. Disease Surveillance, 2019, 34(7): 593-598. doi: 10.3784/j.issn.1003-9961.2019.07.005
Citation: Jianguo Xu. Reverse microbial etiology[J]. Disease Surveillance, 2019, 34(7): 593-598. doi: 10.3784/j.issn.1003-9961.2019.07.005

反向病原学

doi: 10.3784/j.issn.1003-9961.2019.07.005
详细信息
    作者简介:

    徐建国,男,山西省平陆县人,中国工程院院士,主要从事医学微生物、新发突发传染病的研究工作

    通讯作者:

    徐建国,Tel:010-58900789,Email:xujianguo@icdc.cn

Reverse microbial etiology

More Information
  • 摘要: 微生物来到地球的时间比人类早得多,不可能是为了“致病”人类而存在的。 微生物为了生存而具有多种功能,其中一些可危害人类,引起疾病。但还有大量的微生物没有被发现。 未来重大新发传染病的挑战,是应对新的病原体。 因此,我们提出反向病原学。 主要内容包括:(1)发现、分离、命名新的微生物;(2)评估新发现微生物的潜在致病性或者公共卫生意义;(3)提出未来可能引起新发突发传染病的新微生物目录; (4)研究检测、诊断、治疗、预防控制的技术、方法、措施、策略等;(5)预防发生严重急性呼吸综合征(SARS)样的重大新发突发传染病。
  • [1] Xu JG. Reverse microbial etiology: a research field for predicting and preventing emerging infectious diseases caused by an unknown microorganism[J]. J Biosaf Biosecur, 2019,1(1):19–21. DOI: 10.1016/j.jobb.2018.12.005.
    [2] Levine MM, Xu JG, Kaper JB, et al. A DNA probe to identify enterohemorrhagic Escherichia coli of O157: H7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome[J]. J Infect Dis, 1987,156(1):175–182. DOI: 10.1093/infdis/156.1.175.
    [3] 徐建国, 程伯鲲, 冯丽萍, 等. 肠出血性大肠埃希菌引起的溶血性尿毒综合征患者血清抗体调查[J]. 中华流行病学杂志,2002,23(2):87–91. DOI: 10.3760/j.issn:0254−6450.2002.02.011.

    Xu JG, Cheng BK, Feng LP, et al. Serological investigations on patients with hemolytic uremic syndromes due to enterohemorrhagic Escherichia coli O157: H7 infection[J]. Chin J Epidemiol, 2002,23(2):87–91. DOI: 10.3760/j.issn:0254−6450.2002.02.011.
    [4] Xu JG, Cheng BK, Jing HQ. Escherichia coli O157: H7 and shiga-like-toxin- producing Escherichia Coli in China[J]. World J Gastroenterol, 1999,5(3):191–194. DOI: 10.3748/wjg.v5.i3.191.
    [5] Li H, Zhang PH, Huang Y, et al. Isolation and identification of Rickettsia raoultii in human cases: a surveillance study in 3 medical centers in China[J]. Clin Infect Dis, 2018,66(7):1109–1115. DOI: 10.1093/cid/cix917.
    [6] 逄波, 景怀琦, 郑翰, 等. 我国部分产生志贺毒素肠出血性大肠埃希菌O157:H7脉冲电场凝胶电泳分型[J]. 中华流行病学杂志,2002,23(2):123–126. DOI: 10.3760/j.issn:0254−6450.2002.02.013.

    Pang B, Jing HQ, Zheng H, et al. Molecular typing of Shiga-toxin producing Escherichia coli O157:H7 isolated in China with pulsed field gel electrophresis[J]. Chin J Epidemiol, 2002,23(2):123–126. DOI: 10.3760/j.issn:0254−6450.2002.02.013.
    [7] Ye CY, Zhu XP, Jing HQ, et al. Streptococcus suis sequence type 7 outbreak, Sichuan, China[J]. Emerg Infect Dis, 2006,12(8):1203–1208. DOI: 10.3201/eid1708.060232.
    [8] Yu HJ, Jing HQ, Chen ZH, et al. Human Streptococcus suis outbreak, Sichuan, China[J]. Emerg Infect Dis, 2006,12(6):914–920. DOI: 10.3201/eid1206.051194.
    [9] Zhang LJ, Liu Y, Ni DX, et al. Nosocomial transmission of human granulocytic anaplasmosis in China[J]. JAMA, 2008,300(19):2263–2270. DOI: 10.1001/jama.2008.626.
    [10] Morse SS, Mazet JAK, Woolhouse M, et al. Prediction and prevention of the next pandemic zoonosis[J]. Lancet, 2012,380(9857):1956–1965. DOI: 10.1016/S0140−6736(12)61684−5.
    [11] Anthony SJ, Epstein JH, Murray KA, et al. A strategy to estimate unknown viral diversity in mammals[J]. MBio, 2013,4(5):e00598–13. DOI: 10.1128/mBio.00598−13.
    [12] Yarza P, Yilmaz P, Pruesse E, et al. Uniting the classification of cultured and uncultured bacteria and archaea using 16S rRNA gene sequences[J]. Nat Rev Microbiol, 2014,12(9):635–645. DOI: 10.1038/nrmicro3330.
    [13] Konstantinidis KT, Rosselló-Móra R. Classifying the uncultivated microbial majority: a place for metagenomic data in the Candidatus proposal[J]. Syst Appl Microbiol, 2015,38(4):223–230. DOI: 10.1016/j.syapm.2015.01.001.
    [14] Rosselló-Móra R, Amann R. Past and future species definitions for Bacteria and Archaea[J]. Syst Appl Microbiol, 2015,38(4):209–216. DOI: 10.1016/j.syapm.2015.02.001.
    [15] Bai XN, Lu S, Yang J, et al. Precise fecal microbiome of the herbivorous tibetan antelope inhabiting high-altitude alpine plateau[J]. Front Microbiol, 2018,9:2321. DOI: 10.3389/fmicb.2018.02321.
    [16] Poulin R. Parasite biodiversity revisited: frontiers and constraints[J]. Int J Parasitol, 2014,44(9):581–589. DOI: 10.1016/j.ijpara.2014.02.003.
    [17] Poulin R, Morand S. The diversity of parasites[J]. Q Rev Biol, 2000,75(3):277–293. DOI: 10.1086/393500.
    [18] Dobson A, Lafferty KD, Kuris AM, et al. Homage to Linnaeus: how many parasites? How many hosts?[J]. Proc Natl Acad Sci USA, 2008,105(Suppl 1):11482–11489. DOI: 10.1073/pnas.0803232105.
    [19] Prakash PY, Irinyi L, Halliday C, et al. Online databases for taxonomy and identification of pathogenic fungi and proposal for a cloud-based dynamic data network platform[J]. J Clin Microbiol, 2017,55(4):1011–1024. DOI: 10.1128/JCM.02084−16.
    [20] Hernández-Santos N, Klein BS. Through the scope darkly: the gut mycobiome comes into focus[J]. Cell Host Microbe, 2017,22(6):728–729. DOI: 10.1016/j.chom.2017.11.013.
    [21] Hallen-Adams HE, Suhr MJ. Fungi in the healthy human gastrointestinal tract[J]. Virulence, 2017,8(3):352–358. DOI: 10.1080/21505594.2016.1247140.
    [22] Dai XY, Shang GB, Lu S, et al. A new subtype of eastern tick-borne encephalitis virus discovered in Qinghai-Tibet Plateau, China[J]. Emerg Microbes Infect, 2018,7:74. DOI: 10.1038/s41426−018−0081−6.
    [23] Jia N, Jiang JF, Huo QB, et al. Rickettsia sibirica subspecies sibirica BJ-90 as a cause of human disease[J]. N Engl J Med, 2013,369(12):1176–1178. DOI: 10.1056/NEJMc1303625.
    [24] Li H, Zheng YC, Ma L, et al. Human infection with a novel tick-borne Anaplasma species in China: a surveillance study[J]. Lancet Infect Dis, 2015,15(6):663–670. DOI: 10.1016/S1473−3099(15)70051−4.
    [25] Li CX, Shi M, Tian JH, et al. Unprecedented genomic diversity of RNA viruses in arthropods reveals the ancestry of negative-sense RNA viruses[J]. eLife, 2015,4:e05378. DOI: 10.7554/eLife.05378.
    [26] Jiang JF, Zheng YC, Jiang RR, et al. Epidemiological, clinical, and laboratory characteristics of 48 cases of " Babesia venatorum” infection in China: a descriptive study[J]. Lancet Infect Dis, 2015,15(2):196–203. DOI: 10.1016/S1473-3099(14)71046−1.
    [27] Liu QY, Xu WB, Lu S, et al. Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior[J]. Front Med, 2018,12(1):3–22. DOI: 10.1007/s11684−017−0605−9.
    [28] Shi M, Lin XD, Tian JH, et al. Redefining the invertebrate RNA virosphere[J]. Nature, 2016,540(7634):539–543. DOI: 1038/nature20167.
    [29] Cao L, Fu SH, Lu Z, et al. Detection of west nile virus infection in viral encephalitis cases, China[J]. Vector Borne Zoonotic Dis, 2019,19(1):45–50. DOI: 10.1089/vbz.2018.2275.
    [30] Cao L, Fu SH, Lv Z, et al. West Nile virus infection in suspected febrile typhoid cases in Xinjiang, China[J]. Emerg Microbes Infect, 2017,6(6):e41. DOI: 10.1038/emi.2017.27.
    [31] Fu SH, Song S, Liu H, et al. ZIKA virus isolated from mosquitoes: a field and laboratory investigation in China, 2016[J]. Sci China Life Sci, 2017,60(12):1364–1371. DOI: 10.1007/s11427−017−9196−8.
    [32] Ge XY, Li JL, Yang XL, et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor[J]. Nature, 2013,503(7477):535–538. DOI: 10.1038/nature12711.
    [33] Li K, Lin XD, Wang W, et al. Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China[J]. Virology, 2015,476:37–42. DOI: 10.1016/j.virol.2014.11.026.
    [34] Blasdell KR, Duong V, Eloit M, et al. Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia[J]. eLife, 2016,5:e13135. DOI: 10.7554/eLife.13135.
    [35] Wei R, Liu HB, Jongejan F, et al. Cultivation of Anaplasma ovis in the HL-60 human promyelocytic leukemia cell line[J]. Emerg Microbes Infect, 2017,6(9):e83.
    [36] Qin XC, Shi M, Tian JH, et al. A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors[J]. Proc Natl Acad Sci USA, 2014,111(18):6744–6749. DOI: 10.1073/pnas.1324194111.
    [37] Taniguchi S. Detection of Jingmen tick virus in human patient specimens: emergence of a new tick-borne human disease?[J]. EBioMedicine, 2019,43:18–19. DOI: 10.1016/j.ebiom.2019.04.034.
    [38] Jia N, Liu HB, Ni XB, et al. Emergence of human infection with Jingmen tick virus in China: a retrospective study[J]. EBioMedicine, 2019,43:317–324. DOI: 10.1016/j.ebiom.2019.04.004.
    [39] Wang ZD, Wang B, Wei F, et al. A New segmented virus associated with human febrile illness in China[J]. N Engl J Med, 2019,380(22):2116–2125. DOI: 10.1056/NEJMoa1805068.
    [40] Shi M, Lin XD, Vasilakis N, et al. Divergent viruses discovered in arthropods and vertebrates revise the evolutionary history of the Flaviviridae and related viruses[J]. J Virol, 2016,90(2):659–669. DOI: 10.1128/JVI.02036−15.
    [41] Liu S, Jin D, Lan RT, et al. Escherichia marmotae sp. nov., isolated from faeces of Marmota himalayana[J]. Int J Syst Evol Microbiol, 2015,65(7):2130–2134. DOI: 10.1099/ijs.0.000228.
    [42] Meng XL, Lu S, Yang J, et al. Metataxonomics reveal vultures as a reservoir for Clostridium perfringens[J]. Emerg Microbes Infect, 2017,6(2):e9. DOI: 10.1038/emi.2016.137.
  • 加载中
计量
  • 文章访问数:  12086
  • HTML全文浏览量:  2402
  • PDF下载量:  244
  • 被引次数: 0
出版历程
  • 收稿日期:  2019-06-25
  • 网络出版日期:  2019-07-03
  • 刊出日期:  2019-07-01

目录

    /

    返回文章
    返回

    在线交流

    防诈骗公告

    近期有不法分子以本刊编辑身份添加作者微信,请务必提高警惕!本刊关于稿件的一切事项通知均采用编辑部唯一邮箱(jbjc@icdc.cn)和座机(010-58900732)联系作者,且在录用稿件后仅收取版面费,无其他任何名目费用(如审稿费和加急费等),非编辑部邮箱发送的本刊收费用通知等均为诈骗,不要随意汇入款项!如有可疑及时致电编辑部核实确认!