李昌昆, 郑文龙, 辛鹏, 李静, 范莉莉. 天津市成年居民血脂异常和糖尿病患病关系研究[J]. 疾病监测, 2020, 35(8): 706-711. DOI: 10.3784/j.issn.1003-9961.2020.08.008
引用本文: 李昌昆, 郑文龙, 辛鹏, 李静, 范莉莉. 天津市成年居民血脂异常和糖尿病患病关系研究[J]. 疾病监测, 2020, 35(8): 706-711. DOI: 10.3784/j.issn.1003-9961.2020.08.008
Changkun Li, Wenlong Zheng, Peng Xin, Jing Li, Lili Fan. Relationship between dyslipidemia and diabetes mellitus in adults in Tianjin[J]. Disease Surveillance, 2020, 35(8): 706-711. DOI: 10.3784/j.issn.1003-9961.2020.08.008
Citation: Changkun Li, Wenlong Zheng, Peng Xin, Jing Li, Lili Fan. Relationship between dyslipidemia and diabetes mellitus in adults in Tianjin[J]. Disease Surveillance, 2020, 35(8): 706-711. DOI: 10.3784/j.issn.1003-9961.2020.08.008

天津市成年居民血脂异常和糖尿病患病关系研究

Relationship between dyslipidemia and diabetes mellitus in adults in Tianjin

  • 摘要:
    目的探讨天津市成年居民血脂异常与糖尿病患病情况之间的关系。
    方法本研究为现况研究,采用多阶段整群随机抽样方法,抽取4 479名年龄≥18岁的天津市居民进行相关研究,血脂异常与糖尿病关系采用多因素非条件logistic回归方法分析。
    结果发生血脂异常的天津市成年居民患病率为30.65%,其中总胆固醇(TC)边缘升高率为22.73%,升高率为7.08%;甘油三酯(TG)边缘升高率为12.75%,升高率为14.18%;低密度脂蛋白胆固醇(LDL-C)边缘升高率为18.91%;高密度脂蛋白胆固醇(HDL-C)降低率为15.61%;糖尿病患病率为13.31%,其中TC边缘升高者的糖尿病患病率为18.47%,TC升高者的糖尿病患病率为27.76%;TG边缘升高者的糖尿病患病率为19.26%,TG升高者的糖尿病患病率为30.55%;LDL-C边缘升高者的糖尿病患病率为16.88%;HDL-C降低者的糖尿病患病率为18.45%。 研究人群的TC、TG和LDL-C均与空腹血糖呈正相关关系(r=0.210、0.353、0.109,均P<0.001),HDL-C与空腹血糖之间是负相关关系(r=−0.069,P<0.001)。 血脂异常是天津市成年居民糖尿病发病的独立危险因素,其OR值(95%CI)为2.28(1.89~2.75);TC升高、TG升高和HDL-C降低是天津市成年居民糖尿病发病的独立危险因素,其OR值(95%CI)分别为1.68(1.25~2.26)、2.88(2.32~3.58)、1.38(1.10~1.75);TC边缘升高和TG边缘升高是天津市成年居民糖尿病发病的独立危险因素,其OR值(95%CI)分别为1.27(1.03~1.57)、1.66(1.28~2.15)。
    结论天津市成年居民血脂异常和糖尿病密切相关,随着血脂水平的升高糖尿病的患病风险逐渐升高,应对血脂异常和糖尿病采取综合防控措施。

     

    Abstract:
    ObjectiveTo investigate the relationship between dyslipidemia and diabetes mellitus in adults in Tianjin.
    MethodsA total of 4 479 local adults aged ≥18 years selected through multi-stratified clustering sampling in Tianjin were surveyed with a questionnaire. Multifactor Logistic regression model was used to analyze the relationship between dyslipidemia and diabetes mellitus.
    ResultsThe overall prevalence rates of dyslipidemia and diabetes mellitus in the adults were 30.65% and 13.31%, respectively. The overall prevalence rates of borderline high total cholesterol (TC), borderline high triglyceridemia (TG) and borderline high LDL-C were 22.73%, 12.75% and 18.91%. The overall prevalence rates of hypercholesterolemia, hypertriglyceridemia and low HDL-C lipidemia were 7.08%, 14.18% and 15.61%, respectively. The correlation analysis indicated that fasting blood glucose level had positive correlations with TC, TG and LDL-C levels (r=0.210, P<0.001; r=0.353, P<0.001; r=0.109, P<0.001), but negative correlation with HDL-C level (r=−0.069, P<0.001). Dyslipidemia was an independent risk factor of diabetes mellitus in the adults, the odds ratio was 2.28 (95% CI: 1.89–2.75). Hypercholesterolemia, hypertriglyceridemia and low HDL-C lipidemia were independent risk factors of diabetes mellitus in the adults, the odds ratios were 1.68 (95% CI: 1.25–2.26), 2.88 (95% CI: 2.32–3.58) and 1.38 (95% CI: 1.10–1.75), respectively. Borderline high TC and borderline high TG were independent risk factors of diabetes mellitus in the adults, the odds ratios were 1.27 (95% CI: 1.03–1.57) and 1.66 (95% CI: 1.28–2.15), respectively.
    ConclusionDyslipidemia is closely associated with diabetes mellitus in adults in Tianjin. The risk for diabetes mellitus increases gradually with the increase of blood lipid level. Comprehensive prevention and control of dyslipidemia and diabetes mellitus should be carried out.

     

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