Abstract:
Objective To understand the epidemiological and clinical characteristics of G9P8 group A rotavirus (RVA) in hospitalized children with diarrhea in China.
Methods The data of viral diarrhea surveillance network in China from January 2011 to December 2019 were collected, EpiData 3.0 software were used for data collection of viral diarrhea monitoring network, Excel 2010 software were used for data collation, and SPSS 26.0 software was used for data analysis.
Results From January 2011 to December 2019, a total of 47 386 specimens of hospitalized children with acute gastroenteritis under 5 years old were collected by the viral diarrhea surveillance network in China. The positive rate of G9P8 RVA was 54.50％ (8 149/14 952).The positive rate of G9P8 RVA in male children was lower than in female children. The epidemic season is autumn and winter. Compared with non-G9P8 RVA children, G9P8 RVA children had more severe and higher proportion of fever (59.79％, 4 872/8 149), vomiting (53.87％, 4 390/8 149), diarrhea (92.93％, 7 573/8 149), respiratory symptoms (29.30％, 2 388/8 149), neurological symptoms (2.07％, 169/8 149), rash, pneumonia and sepsis (8.21％, 669/8 149) .
Conclusion From January 2011 to December 2019, G9P8 RVA gradually became the main predominant in China. The autumn and winter were G9P8 RVA seasonal peaks, and the symptoms of G9P8 RVA were more severe. This study provides data support for the prevention and control of G9P8 RVA, and reference for the selection of rotavirus vaccine strain.
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