蒋艳, 王静, 秦天, 连星星, 汤睿智, 卢忠心, 徐建国. 大环内酯耐药卡他莫拉菌肺炎的危险因素及临床特征[J]. 疾病监测, 2022, 37(5): 635-640. DOI: 10.3784/jbjc.202111230604
引用本文: 蒋艳, 王静, 秦天, 连星星, 汤睿智, 卢忠心, 徐建国. 大环内酯耐药卡他莫拉菌肺炎的危险因素及临床特征[J]. 疾病监测, 2022, 37(5): 635-640. DOI: 10.3784/jbjc.202111230604
Jiang Yan, Wang Jing, Qin Tian, Lian Xingxing, Tang Ruizhi, Lu Zhongxin, Xu Jianguo. Risk factors and clinical characteristics of macrolide resistance Moraxella catarrhalis pneumonia[J]. Disease Surveillance, 2022, 37(5): 635-640. DOI: 10.3784/jbjc.202111230604
Citation: Jiang Yan, Wang Jing, Qin Tian, Lian Xingxing, Tang Ruizhi, Lu Zhongxin, Xu Jianguo. Risk factors and clinical characteristics of macrolide resistance Moraxella catarrhalis pneumonia[J]. Disease Surveillance, 2022, 37(5): 635-640. DOI: 10.3784/jbjc.202111230604

大环内酯耐药卡他莫拉菌肺炎的危险因素及临床特征

Risk factors and clinical characteristics of macrolide resistance Moraxella catarrhalis pneumonia

  • 摘要:
      目的  了解大环内酯耐药卡他莫拉菌(MRMC)肺炎患者的临床特征,探讨其患病的危险因素。
      方法  对2013年1月至2022年1月的32例MRMC肺炎患者和114例大环内酯敏感卡他莫拉菌(MSMC)肺炎患者信息进行回顾分析。
      结果  卡他莫拉菌肺炎患者以男性为主(71.92%),≥65岁者居多(67.12%),冬春季高发(64.38%)。 多因素logistic回归分析结果显示,女性(OR=2.77, 95%CI: 1.18~6.47)和陈旧性肺结核病史(OR=5.95, 95%CI: 1.31~31.57)是感染MRMC肺炎的独立危险因素。 MRMC组患者发热(OR=2.87, 95%CI: 1.09~7.46)、C反应蛋白升高(OR=2.65, 95%CI: 1.12~6.63)、支气管炎(OR=4.00, 95%CI: 1.54~11.52)和肺气肿影像学表现(OR=5.73, 95%CI: 1.94~19.56)的比例显著高于MSMC组。
      结论  女性和陈旧性肺结核病史是感染MRMC肺炎的独立危险因素,且MRMC组患者的症状、炎症和影像学表现更严重,应关注其临床诊治。

     

    Abstract:
      Objective  To explore the clinical characteristics and risk factors of macrolide resistance Moraxella catarrhalis (MRMC) pneumonia.
      Methods  From January 2013 to January 2022, the information of 32 patients with MRMC pneumonia and 114 patients with macrolides sensitive Moraxella catarrhalis (MSMC) pneumonia were retrospectively analyzed.
      Results  The patients with Moraxella catarrhalis pneumonia were mainly men (71.92%) and aged ≥65 years (67.12%). The incidence rate was high in winter and spring (64.38%). Multivariate logistic regression analysis showed that being woman (OR=2.77, 95% CI: 1.18–6.47) and the history of tuberculosis (OR=5.95, 95% CI: 1.31–31.57) were independent risk factors for MRMC pneumonia. The percentage of patients with fever (OR=2.87, 95% CI: 1.09–7.46), abnormal C-reactive protein (OR=2.65, 95% CI: 1.12–6.63), bronchitis (OR=4.00, 95% CI: 1.54–11.52), and emphysema (OR=5.73, 95% CI: 1.94–19.56) increased significantly in the MRMC group compared with the MSMC group.
      Conclusion  Being woman and the history of tuberculosis were independent risk factors for MRMC pneumonia, and patients in the MRMC group had more severe symptoms, inflammation and pulmonary imaging manifestations, suggesting that attention should be paid to the clinical diagnosis and treatment of MRMC pneumonia.

     

/

返回文章
返回