Objective  To assess the risk of public health emergencies, both the indigenous ones and the imported ones, which might occur in the mainland of China in May 2022.

  Methods   An internet based expert counsel was conducted to analyze the surveillance data of public health emergencies and priority communicable diseases in China reported through different channels, and the experts in all provincial centers for disease control and prevention attended this video conference.

  Results   It is expected that the overall situation of COVID-19 in China will continue to be stable and eased in May. Although the risk of the situation worsening may still exist. Considering the potential risks, it is still necessary to quicken local epidemic response, to optimize prevention and control measurement in time and to get fully prepared before the epidemic starts. It is also expected that toxic mushroom poisoning events will gradually increase since May. Acute and severe hepatitis of unknown origin in children are reported in U.K. and multiple other countries, whose further related surveillance and research progress need to be tracked.

  Conclusion   Special attention should be paid to COVID-19. General attentions should be paid to toxic mushroom poisoning events.