Objective To analyze the trend of stroke disease burden and its major risk factors in Zhejiang province from 1990 to 2019 and provide evidence for the prevention and control of stroke.
Methods By using 2019 Global Burden of Disease (GBD) data, the years lived with disability (YLDs), years of life lost (YLLs) and disability adjusted life years (DALYs) of stroke were calculated to describe the disease burden of stroke in Zhejiang from 1990 to 2019, and the changing trend of the disease burden and major risk factors of stroke were analyzed. Meanwhile, the findings were compared with other areas in China and other regions in the world with different Socio-Demographic Index (SDI).
Results From 1990 to 2019, the YLL rate and DALY rate of stroke in Zhejiang showed decreasing trends and the rate of change was −17.4% and −9.6%. However, the YLD rate increased by 78.3% steadily. In 2019, the YLL rate, YLD rate and DALY rate of stroke in Zhejiang were 1570.8 per 100000, 301.7 per 100000 and 1872.5 per 100000 respectively, which were highest in age group ≥70 years and lowest in age group 15−49 years. In 2019, the YLL rate and DALY rate were significantly higher in men than in women, but men and women had same YLD rate. The type of stroke had gradually shifted from ischemic stroke to hemorrhagic stroke. Compared with other areas in China and other regions in the world with different SDI, the disease burden of stroke in Zhejiang was at a relatively low level the age-standardized YLL rate and age-standardized DALY rate of stroke were only higher than those in areas (regions) with high SDI. In 2019, the main risk factors for stroke were hypertension, ambient particulate matter pollution, diet high in sodium, smoking and hyperglycemia. Compared with 1990, the influence of behavioral and environmental risk factors increased.
Conclusion The disease burden of stroke in Zhejiang generally showed a downward trend, the situation was better than that in most regions of the world. The disease burden in age group 70 years and men were still serious. More efforts are needed for the prevention and control of stroke. Differentiated and precise methods need to be taken to further reduce the disease burden of stroke in Zhejiang.