Objective  To analyze the detection, prevalence and spatiotemporal distribution of hepatitis B in pregnant women in different areas of Xinjiang and provide evidence for the hepatitis B prevention and control in pregnant women.

  Methods  The data were collected from the information management system for preventing mother to child transmission of AIDS, syphilis and hepatitis B, and software SPSS 25.0 and Geoda 1.14 were used to analyze the annual changes of detection rate, positive detection rate and spatiotemporal distribution of positive detection rate of hepatitis B in pregnant women in Xinjiang from 2013 to 2021.

  Results  From 2013 to 2021, the detection rate of hepatitis B in pregnant women in Xinjiang increased from 93.68% to 99.99%, the detection rate of HBsAg during pregnancy increased from 69.33% to 99.40%, the injection rate of hepatitis B immunoglobulin in newborns of mothers with hepatitis B increased from 96.11% to 99.79%, and the positive detection rate in pregnant women decreased from 2.60% in 2013 to 2.36% in 2021. Three areas with high average hepatitis B positive detection rates were Boertala, Karamay and Bayingoleng prefectures, with positive rates exceeding 3.40%, while the three areas with low average hepatitis B positive detection rates were Hotan, Altay and Aksu, with positive rates below 1.70%. Moran index analysis showed no spatial clustering of hepatitis B cases in pregnant women in Xinjiang.

  Conclusion  The detection rate of hepatitis B in pregnant women in Xinjiang remained to be high, and the detection rate during pregnancy increased year by year. Although the positive detection rate of hepatitis B in pregnant women decreased slightly, it did not show a downward trend, and there were large area specific differences, showing an area specific random distribution. The prevention and control of hepatitis B in pregnant women should be strengthened to further reduce the mother to child transmission.