Abstract:
Objective To investigate the incidence of adverse pregnancy outcomes of HIV-infected pregnant women and its influencing factors in Guangdong province and provide evidence to protect the health of HIV-infected pregnant women and exposed children.
Methods The information about3 438 HIV infected pregnant women in all districts and counties of Guangdong from 2011 to 2020 were analyzed by χ2 test and non-conditional logistic regression model.
Results The incidence rate of adverse pregnancy outcome in HIV infected pregnant women was 27.78% (955/3 438). The differences in education level, initial detection time, transmission route, parity, infection confirmation time and gestational hypertension on the incidence of adverse pregnancy outcome had significance (P<0.05). Multivariate logistic regression analysis showed that the ORs of adverse pregnancy outcomes in HIV-infected pregnant women who were infected by injecting drug use, had infection confirmation during or after delivery and had gestational hypertension were 1.65 (1.04−2.58), 0.61 (0.48−0.78) and 2.27 (1.35−3.80).
Conclusion Transmission route, infection confirmation time and gestational hypertension were related to adverse pregnancy outcomes of HIV-infected women in Guangdong during this period. It is necessary to attach great importance to the reproductive health of HIV-infected pregnant women, provide high-quality consultation and pregnancy health care services to protect the health of HIV-infected pregnant women and improve pregnancy outcomes.
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