Objective   To assess the global epidemic of Coronavirus disease 2019 (COVID-19) in November 2022 and the risk of importation.

  Methods   According to the daily COVID-19 data publicly released by Johns Hopkins University, combined with the policy stringency index published by the University of Oxford, an epidemiological description method was used to provide a comprehensive and timely assessment of the global epidemic risk through a general overview, a comprehensive assessment of the epidemic trends in WHO regions and key countries, as well as a comprehensive analysis of the epidemic and prevention and control policies in 14 neighboring countries. The assessment results for each country are expressed as “countries of global concern”, “countries of the general concern in each WHO sub-region” and “neighboring countries of special concern”.

  Results  Compared with October 2022, the global monthly new confirmed cases increased by 1.6%, and the global monthly new deaths decreased by 1.6%. Except for the Europe region (−41.4%) and Eastern Mediterranean region (−34.1%), the number of new cases in the remaining regions increased to varying degrees (between 19.6% and 122.2%). Except for South-East Asia region (171.8%) and Western Pacific region (17.5%), the number of new deaths in the remaining regions decreased to varying degrees (between 2.4% and 27.3%). Japan, Korea, America, China, Brazil, Australia and Greece are countries of global concern.

  Conclusion  The global daily newly confirmed cases showed an upward trend in November, especially in Americas, Africa and Western Pacific region, which should be paid special attention to, timely communicate and adjusted measures.