2022年河北省张家口市1起呼吸道病毒混合感染疫情的流行特征分析

祁琳 李越 张海洋 宋文静 李青凤 胡雪倩 王玉玲

祁琳, 李越, 张海洋, 宋文静, 李青凤, 胡雪倩, 王玉玲. 2022年河北省张家口市1起呼吸道病毒混合感染疫情的流行特征分析[J]. 疾病监测, 2023, 38(10): 1268-1272. doi: 10.3784/jbjc.202301020557
引用本文: 祁琳, 李越, 张海洋, 宋文静, 李青凤, 胡雪倩, 王玉玲. 2022年河北省张家口市1起呼吸道病毒混合感染疫情的流行特征分析[J]. 疾病监测, 2023, 38(10): 1268-1272. doi: 10.3784/jbjc.202301020557
Qi Lin, Li Yue, Zhang Haiyang, Song Wenjing, Li Qingfeng, Hu Xueqian, Wang Yuling. Epidemiological characteristics of an outbreak of mixed infections of respiratory viruses in Zhangjiakou of Heibei, in 2022[J]. Disease Surveillance, 2023, 38(10): 1268-1272. doi: 10.3784/jbjc.202301020557
Citation: Qi Lin, Li Yue, Zhang Haiyang, Song Wenjing, Li Qingfeng, Hu Xueqian, Wang Yuling. Epidemiological characteristics of an outbreak of mixed infections of respiratory viruses in Zhangjiakou of Heibei, in 2022[J]. Disease Surveillance, 2023, 38(10): 1268-1272. doi: 10.3784/jbjc.202301020557

2022年河北省张家口市1起呼吸道病毒混合感染疫情的流行特征分析

doi: 10.3784/jbjc.202301020557
详细信息
    作者简介:

    祁琳,女,山东省安丘市人,主管护师,在读硕士,主要从事呼吸系统疾病研究. Email:qilin301@126.com

    李越,男,湖北省恩施市人,医师,军事预防医学硕士,主要从事呼吸道传染病研究. Email:liyue19930705@vip.qq.com

    通讯作者:

    王玉玲,Tel:010–66939475,Email:wangyuling301@163.com

  • 中图分类号: R211;R183.3

Epidemiological characteristics of an outbreak of mixed infections of respiratory viruses in Zhangjiakou of Heibei, in 2022

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  • 摘要:   目的  探讨2022年河北省张家口市某工厂一起由腺病毒55型、乙型流感病毒、甲型流感病毒、副流感病毒3型混合感染暴发疫情的流行病学特征,探究流行的危险因素,为疫情早期预警和防控提供科学依据。  方法  对该厂区可能受疫情影响的所有人员进行现场流行病学调查,采集咽拭子进行病原体核酸筛查,并定期开展多轮病原筛查,持续监测病原结果。  结果  经实验室检测确认该起疫情由腺病毒55型(感染273例)、乙型流感病毒(感染225例)、副流感病毒3型(感染40例)、甲型流感病毒(感染9例)混合感染引起,共导致547人感染。 疫情主要流行于青年男性工人群体,吸烟者感染率高于非吸烟者。 乙型流感病毒感染者的症状最为明显,发热和全身症状比例较高。  结论  人群密集的工厂内吸烟的青年工人群体为4类呼吸道病毒的主要感染对象。 应重点关注人群密集场所的健康教育、症状监测和病原筛查,控制呼吸道传染病流行。
  • 图  1  2022年河北省张家口市某厂区ARIs发病时间分布

    Figure  1.  Time distribution of acute respiratory infection cases in a factory of Zhangjiakou, Heibei, in 2022

    表  1  2022年河北省张家口市某厂区急性呼吸道病毒感染区域分布

    Table  1.   Area specific distribution of infection rates of respiratory viruses in a factory of Zhangjiakou, Heibei, in 2022

    主要活动场所人数腺病毒55型乙型流感病毒副流感病毒3型甲型流感病毒
    1车间 832 81 (9.74) 116 (13.94) 3 (0.36) 3 (0.36)
    2车间 874 51 (5.83) 87 (9.95) 14 (1.60) 1 (0.11)
    3车间 858 79 (9.21) 10 (1.17) 3 (0.35) 3 (0.35)
    4车间 882 40 (4.54) 11 (1.25) 14 (1.59) 0 (0.00)
    后勤宿舍 87 22 (25.29) 1 (1.15) 6 (6.90) 2 (2.30)
    保安宿舍 55 0 (0.00) 0 (0.00) 0 (0.00) 0 (0.00)
    办公大楼 186 0 (0.00) 0 (0.00) 0 (0.00) 0 (0.00)
    χ2
    P <0.001 <0.001 <0.001 0.493
    注:括号外数据为阳性例数(例),括号内数据为感染率(%);–. 使用Fisher精确概率法计算
    下载: 导出CSV

    表  2  2022年河北省张家口市某厂区急性呼吸道病毒感染率人群分布特征

    Table  2.   Population distribution of infection rates of respiratory viruses in a factory of Zhangjiakou, Heibei, in 2022

     特征腺病毒55型(n=273)乙型流感病毒(n=225)副流感病毒3型(n=40)甲型流感病毒(n=9)
    年龄组(岁)
     <20 (n=709)63 (8.89)55 (7.76)5 (0.71)1 (0.14)
     20~ (n=2 715)205 (7.55)165 (6.08)35 (1.29)7 (0.26)
     30~ (n=200)4 (2.00)5 (2.50)0 (0.00)1 (0.50)
     ≥40 (n=150)1 (0.67)0 (0.00)0 (0.00)0 (0.00)
     χ221.0917.93
     P<0.001<0.0010.1540.675
    人员类别
     车间管理(n=436)23 (5.26)16 (3.66)5 (1.14)4 (0.92)
     车间工人(n=3 057)249 (8.14)206 (6.74)35 (1.14)3 (0.10)
     厂区管理(n=96)0 (0.00)3 (3.13)0 (0.00)1 (1.04)
     后勤人员(n=185)1 (0.56)0 (0.00)0 (0.00)1 (0.54)
     χ226.1120.48
     P<0.001<0.0010.4880.004
    是否吸烟
     不吸烟(n=2 866)45 (1.57)31 (1.08)6 (0.21)0 (0.00)
     吸烟(n=908)228 (25.11)194 (21.37)34 (3.74)9 (0.99)
     χ2565.90502.4378.84
     P<0.001<0.001<0.001<0.001
    注:括号外数据为阳性例数(例),括号内数据为感染率(%);–. 使用Fisher精确概率法计算
    下载: 导出CSV

    表  3  2022年河北省张家口市某厂区急性呼吸道病毒感染症状发生率

    Table  3.   Symptoms of acute respiratory infections in a factory of Zhangjiakou, Heibei, in 2022

    症状腺病毒55型(n=166)乙型流感病毒(n=140)副流感病毒3型(n=31)甲型流感病毒(n=6)P
    发热18(10.84)36(25.71)2(6.45)3(50.00)<0.001
    畏寒16(9.64)32(22.86)0(0.00)2(33.33)<0.001
    乏力17(10.24)21(15.00)1(3.23)3(50.00)0.008
    咳嗽59(35.54)60(42.86)7(22.58)2(33.33)0.173
    咽痛60(36.14)76(54.29)5(16.13)1(16.67)<0.001
    鼻塞66(39.76)78(55.71)3(9.68)1(16.67)<0.001
    流涕81(48.80)92(65.71)5(16.13)0(0.00)<0.001
    胸闷30(18.07)35(25.00)0(0.00)0(0.00)0.148
    呼吸困难2(1.20)2(1.43)0(0.00)1(16.67)0.914
    头痛2(1.20)14(10.00)1(3.23)2(33.33)0.003
    肌肉酸痛7(4.22)24(17.14)0(0.00)3(50.00)0.002
    恶心2(1.20)4(2.86)0(0.00)0(0.00)0.584
    呕吐5(3.01)2(1.43)0(0.00)0(0.00)0.611
    结膜炎0(0.00)0(0.00)0(0.00)0(0.00)
    腹泻7(4.22)2(1.43)1(3.23)1(16.67)0.140
    肺炎0(0.00)0(0.00)0(0.00)0(0.00)
    哮喘0(0.00)0(0.00)0(0.00)0(0.00)
    注:括号外数据为阳性例数(例),括号内数据为发生率(%);–. 无数据
    下载: 导出CSV
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  • 收稿日期:  2023-01-02
  • 网络出版日期:  2023-07-03
  • 刊出日期:  2023-11-07

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