Objective   To analyze the characteristics and trends of malignant tumors mortality in local population inHaidian district of Beijing from 2010 to 2021, and provide reference for the prevention and control of malignant tumors.

  Methods  The death data of malignant tumors in local residents in Haidian from 2010 to 2021 were collected, and the constituent ratio, crude and standardized mortality rate, year of life lost (YLL) rate and standardized YLL rate were calculated. Joinpoint regression model was used to estimate the average annual trend.

  Results  Malignant tumors ranked first in all causes of death in local residents of Haidian from 2010 to 2021, with deaths accounting for 30.23%. The average annual crude mortality rate standardized mortality rate were 142.47/100 000 and 93.32/100 000 respectively. The crude mortality rate was higher in men than women, the difference was statistically significant (t=11.18, P<0.05), and the standardized mortality rates in all years were higher in men than in women. Compared with 2010, the proportion of malignant tumor deaths in 2021 decreased to 26.77% (−15.37%). The crude mortality of total population, in men and in women showed increasing trends year by year with average annual percentage change (AAPC) of 1.62%, 1.82% and1.42%, respectively (all P<0.01), while the standardized mortality showed decreasing trends year by year with AAPC of −1.50%, −1.13% and −1.85%, respectively (all P<0.01).The top 10 causes of death included lung cancer and digestive system malignant tumor, the top 6 causes of death remained unchanged, i.e. lung cancer, colorectal cancer, liver cancer, gastric cancer, pancreatic cancer and breast cancer. The crude mortality of bladder cancer, breast cancer and colorectal cancer increased significantly (AAPC=4.56%, 3.81%, 3.80%, all P<0.001), and the crude mortality of liver cancer decreased year by year (AAPC=−1.24%, P<0.05). The YLL increased year by year, the change in YLL rate had no significantce (AAPC=0.30%, P>0.05), while the standardized YLL rate showed a downward trend year by year (AAPC=−2.10%, P<0.05). The YLL rates of colorectal cancer, pancreatic cancer, bladder cancer and breast cancer increased year by year (AAPC=2.90%, 2.60%, 3.40%, 1.90%, all P<0.05), but the YLL rates of liver cancer and gastric cancer decreased year by year (AAPC=−2.70% and −1.20%, all P<0.05).

  Conclusion  Lung cancer and digestive system malignant of cancer death in Haidian. In recent years, the rising mortality rate of major malignant tumor has been greatly affected by the aging of the population, but the burden of malignant tumors related to smoking, environmental pollution and poor lifestyle is still heavy. Therefore, it is necessary to take targeted prevention and control measures in different population, for different cancer type and according to cancer incidence trend.