2016-2022年重庆都市圈肺结核患者就诊延迟特征及影响因素分析

Analysis on medical care seeking delay in pulmonary tuberculosis patients and influencing factors in Chongqing metropolitan area, 2016−2022

  • 摘要:
    目的 描述2016—2022年重庆都市圈肺结核患者就诊延迟特征并分析其影响因素,为重庆都市圈肺结核防控提供依据。
    方法 从中国疾病预防控制信息系统的子系统结核病信息管理系统中导出 2016—2022 年重庆市和广安市登记的敏感肺结核患者病案数据,包括年龄、性别、职业、民族、患者来源、并发症、治疗分类、现住址、症状出现日期、首次就诊日期、登记日期、户籍地址类别、重点人群、现诊断地区等。 采用中位数及四分位数间距进行统计描述,就诊延迟率随时间变化的趋势采用 χ2 趋势性检验,就诊延迟影响因素采用χ2检验和logistic回归分析模型。
    结果 2016—2022年重庆都市圈肺结核患者就诊延迟天数中位数为29(9,62)d,年均就诊延迟率为67.11%(81070/120807),且就诊延迟率呈逐年下降趋势(趋势χ2=244.650,P<0.01)。 渝东北区(73.98%)与渝东南区(70.72%)地区就诊延迟率远高于其他地区(χ2=1877.018P<0.001)。 外地户籍[比值比(OR)=1.08,95%置信区间(CI): 1.04~1.12]、被动发现(OR=5.56,95%CI: 5.07~6.11、有合并症(OR=1.13,95%CI: 1.10~1.16)、26~39岁(OR=1.14,95%CI:1.08~1.20)、40~54岁(OR=1.42,95%CI: 1.35~1.49)、55~64岁(OR=1.50,95%CI: 1.41~1.59、≥65岁(OR=1.3895%CI: 1.31~1.47、重点人群(OR=0.94,95%CI: 0.90~0.98)、职业[学生(OR=0.56,95%CI: 0.53~0.60、工人(OR=0.88,95%CI: 0.83~0.940、家务及待业(OR=0.83,95%CI: 0.80~0.87、离退人员(OR=0.86,95%CI: 0.80~0.92、其他(OR=0.65,95%CI: 0.620~0.68]均为就诊延迟影响因素。
    结论 重庆都市圈肺结核患者就诊延迟率逐年下降,各地的肺结核患者就诊延迟时间和就诊延迟率有较大差异,这与不同地区医疗服务水平,医疗可及性,经济交通发展状况以及发病水平有关。 户籍地址、患者来源、合并症、年龄、重点人群、职业等均为就诊延迟影响因素,应对不同因素采取针对性措施。

     

    Abstract:
    Objective To describe the characteristics of delayed medical care seeking in pulmonary tuberculosis (TB) patients and influencing factors in Chongqing metropolitan area, which covers Chongqing municipality and Guang'an prefecture of Sichuan province, from 2016 to 2022, and provide evidence for pulmonary TB prevention and control in this area.
    Methods The medical records data of drug sensitive pulmonary TB patients registered in Chongqing and Guang 'an during 2016−2022, including age, gender, occupation, patient source, complication, treatment type, current address, onset date, the first medical care seeking date, registration date, household registration type, key population and area bring diagnosed, were extracted from the Tuberculosis Information Management System, a subsystem of China Disease Prevention and Control Information System. The median and interquartile intervals were used for statistical description. The trend in medical care seeking delay over time was analyzed with χ2 test. The influencing factors for medical care seeking delay were analyzed with χ2 test and Logistic regression model.
    Results The median delay of medical care seeking was 29 (9,62) days in pulmonary TB patients in Chongqing metropolitan area from 2016 to 2022, and the average annual delay rate was 67.11% (81070/120807), and the delay rate showed a decreasing trend year by year (trend χ2 = 244.650, P < 0.01). The delay rates were much higher in northeast Chongqing (73.98%) and southeast Chongqing (70.72%) than in others (χ2=1877.018, P<0.001). Being resident from other area odds ratio(OR)=1.08, 95% confidence interval (CI): 1.04–1.12, passive detection (OR=5.56, 95%CI: 5.07–6.11), comorbidity (OR=1.13, 95%CI: 1.10–1.16), age 26–39 years (OR=1.14, 95%CI: 1.08–1.20), age 40–54 years (OR=1.42, 95%CI: 1.35–1.49, age 55–64 years (OR=1.50, 95%CI: 1.41–1.59, age ≥65 years (OR=1.38, 95%CI: 1.31–1.47, being in key population (OR=0.94, 95%CI: 0.90–0.98, occupation student (OR=0.56, 95%CI: 0.53–0.60), workers (OR=0.88, 95%CI: 0.83–0.94), unemployment or jobless (OR=0.83, 95%CI: 0.80–0.87), being retirees (OR=0.86, 95%CI: 0.81–0.92) and others (OR=0.65, 95%CI: 0.62–0.68) were the factors for medical care seeking delay.
    Conclusion The delayed rate of medical care seeking in pulmonary TB patients in Chongqing metropolitan area decreased year by year, but the delay days and delay rate varied due to the different medical service level and accessibility, economic and transportation status and pulmonary TB incidence level in this area. Household registration status, patient source, comorbidity, age, key population and occupation were all the factors affecting the timeliness of medical care seeking of pulmonary TB patients, indicating targeted intervention measures should be taken.

     

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