2018-2022年甘肃省≥60岁老年肺结核患者治疗转归情况及影响因素分析

Analysis on treatment outcomes and influencing factors in pulmonary tuberculosis patients aged ≥60 years in Gansu, 2018−2022

  • 摘要:
    目的 分析甘肃省老年肺结核患者治疗转归情况及影响因素,为提升老年肺结核患者成功治疗率提供科学依据。
    方法 从全国结核病信息管理系统中收集2018—2022年甘肃省登记的年龄≥60岁肺结核患者资料,运用logistic回归分析影响老年肺结核患者治疗转归结局影响因素。
    结果 2018—2022年甘肃省共登记老年肺结核患者13170例,成功治疗12219例,成功治疗率为92.78%,成功治疗率呈上升趋势(趋势χ2=5.979,P=0.014)。 多因素logistic回归分析显示,男性[比值比(OR)=1.59,95%置信区间(CI):1.39~1.83]、中龄组(70~岁)(OR=1.73,95%CI:1.49~2.01)、高龄组(≥80岁)(OR=2.87,95%CI:2.31~3.57)、复治(OR=1.63,95%CI:1.24~2.14)、病原学阳性(OR=2.50,95%CI:2.13~2.94)和首诊断单位为县级(OR=1.68,95%CI:1.38~2.05)是治疗不成功的危险因素,纳入基层管理(OR=0.68,95%CI:0.59~0.79)的患者容易成功治疗。
    结论 2018—2022年甘肃省老年肺结核患者成功治疗率呈上升趋势,男性、70岁以上、复治、病原学阳性、首诊在县级的人群治疗转归结局较差,提示相关单位和个人要有针对性地加强该部分人群的督导管理服药,进一步提升成功治疗率,降低治疗不成功的发生率。

     

    Abstract:
    Objective To understand the treatment outcomes and influencing factors in pulmonary tuberculosis (TB) patients in the elderly in Gansu province and provide evidence to increase the successful treatment rate of pulmonary TB in the elderly.
    Methods The information about pulmonary tuberculosis patients aged ≥60 registered in Gansu from 2018 to 2022 were collected from National Tuberculosis Information Management System, and logistic regression analysis was used to identify the influencing factors for the treatment outcomes of pulmonary TB in the elderly.
    Results A total of 13170 pulmonary TB patients aged ≥60 years were registered in Gansu from 2018 to 2022, in whom 12219 were successfully treated, the successful treatment rate showed an increasing trend (trend χ2=5.979, P=0.014 ). Multivariate logistic regression analysis showed that being man odds ratio (OR)=1.59, 95% confidence interval (CI): 1.39–1.83, middle-age (70− years old ) (OR=1.73, 95%CI: 1.49–2.01), old age (≥80 years old) (OR=2.87, 95%CI: 2.31–3.57), being retreated (OR=1.63, 95%CI: 1.24–2.14), being etiological positive (OR=2.50, 95% CI: 2.13–2.94), and being diagnosed initially at county level medical institution (OR=1.68, 95%CI: 1.38–2.05) were risk factors for unsuccessful treatment. Basic case management (OR=0.68, 95%CI: 0.59–0.79) was a protective factor for successful treatment.
    Conclusion The successful treatment rate of pulmonary TB in the elderly showed an upward trend in Gansu from 2018 to 2022. The treatment outcomes in men, those aged >70 years, re-treated patients, etiological positive patients, and those with initial diagnosis at the county level medical institutions were relatively poor. It is suggested to strengthen the supervision and management of medication in the treatment of pulmonary TB in the elderly to further increase the successful treatment rate and reduce the incidence of adverse outcomes.

     

/

返回文章
返回