Abstract:
Objective To study the epidemiological characteristics of psittacosis cases in Jiuquan, Gansu and provide evidence for the diagnosis, treatment, prevention and control of psittacosis.
Methods Retrospective study and epidemiological investigation were conducted to collect the incidence, clinical treatment and epidemiological data of psittacosis cases on Jiuquan in 2022－2024. External environmental surveillance was carried out. Metagenomic second-generation sequencing, real-time fluorescent quantitative polymerase chain reaction for nucleic acid detection and whole genome sequencing were used for the detection and genotyping of Chlamydia psitsiti.
Results The sex ratio of 11 cases of psittacosis was 10.00∶1, the mean age of the cases was (60.55±11.13) years, and 5 cases were farmers (45.45%). There were 9 cases with poultry contact history (81.82%), and the average incubation period was (11.11±5.67) days. All the 11 cases had fever (100.00%) and cough (100.00%), 9 cases showed shortness of breath (81.82%) and 8 cases had expectoration (72.73%). There were 10 cases with severe pneumonia (90.91%), and the case fatality rate was 18.18%. The positive rate of Chlamydia psitsiti in external environment samples was 21.74%.
Conclusion Most patients with psittacosis had contacts with birds, the clinical manifestations were non-specific, resulting in difficulty in early identification and diagnosis, and the severe case rate and case fatality rate were high, indicating a heavy disease burden. External environmental surveillance can facilitate the early warning and joint prevention and control is an important measure for the prevention and control of psittacosis.
下载: