内蒙古自治区35~75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究

徐肖倩 夏远 李海玲 张楠 曹宁 张星光

徐肖倩, 夏远, 李海玲, 张楠, 曹宁, 张星光. 内蒙古自治区35~75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究[J]. 疾病监测. doi: 10.3787/jbjc20230020
引用本文: 徐肖倩, 夏远, 李海玲, 张楠, 曹宁, 张星光. 内蒙古自治区35~75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究[J]. 疾病监测. doi: 10.3787/jbjc20230020
Xu Xiaoqian, Xia Yuan, Li Hailing, Zhang Nan, Cao Ning, Zhang Xingguang. Association between central obesity and cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35−75 years in Inner Mongolia[J]. Disease Surveillance. doi: 10.3787/jbjc20230020
Citation: Xu Xiaoqian, Xia Yuan, Li Hailing, Zhang Nan, Cao Ning, Zhang Xingguang. Association between central obesity and cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35−75 years in Inner Mongolia[J]. Disease Surveillance. doi: 10.3787/jbjc20230020

内蒙古自治区35~75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究

doi: 10.3787/jbjc20230020
基金项目: 国家自然科学基金(No. 82160639);内蒙古自治区自然科学基金(No. 2020MS08048);内蒙古自治区自治区高校科研项目(No. NJZY22620)
详细信息
    作者简介:

    徐肖倩,女,内蒙古赤峰市人,硕士,讲师,主要从事慢性病流行病学调查工作,Email:xxq20100@163.com

    通讯作者:

    张星光,Tel:0471−6653387,Email:zxg311@126.com

  • 中图分类号: R211;R181

Association between central obesity and cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35−75 years in Inner Mongolia

Funds: The study was supported by the National Natural Science Foundation of China (No. 82160639), and fund for Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region (No. 2020MS08048) and Inner Mongolia Autonomous Region University Research Project (No. NJZY22620)
More Information
  • 摘要:   目的  分析内蒙古自治区(自治区)35~75岁居民中心型肥胖与心血管代谢性疾病和共病的关联。  方法  选择2015年9月至2017年6月“心血管病高危人群早期筛查与综合干预项目”中内蒙古招募的35~75岁居民为研究对象。采用SPSS 25.0和GraphPad Prism 5软件进行统计分析,采用统计描述、χ2检验和logistic回归分析中心型肥胖对心血管代谢性疾病(高血压、糖尿病、血脂异常)和共病的影响。  结果  内蒙古35~75岁居民中心型肥胖率为66.5%[95%置信区间(CI):66.2%~66.7%],年龄、性别标化率为64.6%。同一个体患有0、1、2和3种心血管代谢性疾病的构成比分别为28.8%、40.5%、23.8%和6.9%。 Logistic回归分析结果显示,轻度中心型肥胖和重度中心型肥胖者高血压、糖尿病、血脂异常、共病的患病风险分别是非中心型肥胖者的1.873和3.093倍、1.876和2.764倍、2.227和3.412倍、2.526和4.419倍(均P<0.001)。  结论  中心型肥胖是内蒙古严重的健康问题,是心血管代谢性疾病和共病的危险因素,可进一步加剧心血管疾病负担。 因此,应加强中心型肥胖的早期筛查和干预。
  • 图  1  内蒙古自治区35~75岁居民心血管代谢性疾病种数构成情况

    Figure  1.  Composition of 35–75 years old residents with 1–3 cardiometabolic diseases in Inner Mongolia (%)

    图  2  内蒙古自治区35~75岁居民心血管代谢性疾病logistic回归分析

    注:OR. 比值比;CI. 置信区间

    Figure  2.  Logistic regression analysis on cardiometabolic diseases in residents aged 35–75 years in Inner Mongolia

    表  1  内蒙古自治区不同特征35~75岁居民中心型肥胖情况

    Table  1.   1Prevalence of central obesity in 35-75 years old residents aged with different characteristics in Inner Mongolia

     分组调查数[人(%)]非中心型肥胖a
    轻度中心型肥胖a重度中心型肥胖aχ2P
    性别 73.967 <0.001
     男性 29 070(41.9) 35.1(34.2~36.0) 37.6(36.7~38.5) 27.3(26.4~28.3)
     女性 40 299(58.1) 32.3(31.5~33.1) 40.4(39.7~41.2) 27.3(26.4~28.1)
    民族 124.221 <0.001
     汉 62 300(89.8) 34.0(33.3~34.6) 39.3(38.7~39.9) 26.7(26.0~27.4)
     蒙 6 019(8.7) 29.4(27.3~31.5) 38.1(36.1~40.1) 32.5(30.4~34.6)
     其他 1 050(1.5) 27.5(22.4~32.7) 40.7(36.0~45.3) 31.8(26.8~36.8)
    年龄组(岁) 215.168 <0.001
     35~ 11 629(16.7) 41.1(39.7~42.5) 37.6(36.2~39.1) 21.3(19.7~22.9)
     45~ 23 431(33.8) 33.0(31.9~34.0) 41.2(40.2~42.1) 25.9(24.8~27.0)
     55~ 23 578(34.0) 30.6(29.6~31.7) 39.3(38.3~40.3) 30.1(29.0~31.1)
     65~75 10 731(15.5) 32.7(31.2~34.3) 36.6(35.1~38.1) 30.7(29.2~32.3)
    居住地 702.793 <0.001
     农村 47 945(69.1) 36.6(35.9~37.3) 37.8(37.1~38.5) 25.6(24.8~26.3)
     城镇 21 424(30.9) 26.5(25.3~27.6) 42.4(41.4~43.4) 31.1(30.0~32.3)
    家庭年收入(万元) 213.545 <0.001
     <1 33 149(47.8) 35.9(35.1~36.8) 38.1(37.3~39.0) 26.0(25.0~26.9)
     1~ 22 709(32.7) 31.8(30.7~32.9) 40.2(39.2~41.2) 28.0(26.9~29.1)
     ≥5 7 919(11.4) 28.5(26.6~30.3) 41.1(39.4~42.8) 30.4(28.6~32.2)
     不知道 5 592(8.1) 32.9(30.7~35.0) 39.2(37.2~41.3) 27.9(25.7~30.1)
    教育水平 901.127 <0.001
     初等及以下 41 568(59.9) 37.0(36.2~37.7) 37.6(36.8~38.3) 25.5(24.6~26.3)
     中等 6 562(9.5) 36.2(34.3~38.2) 40.2(38.3~42.1) 23.6(21.4~25.7)
     高等及以上 13 662(19.7) 24.6(23.1~26.0) 43.3(42.0~44.6) 32.1(30.7~33.5)
     不知道 7 577(10.9) 28.1(26.2~30.0) 40.2(38.4~41.9) 31.7(29.9~33.6)
    农民 468.128 <0.001
     是 32 617(47.0) 37.6(36.7~38.5) 36.8(35.9~37.6) 25.6(24.7~26.6)
     否 36 752(53.0) 29.8(29.0~30.7) 41.4(40.6~42.2) 28.8(27.9~29.6)
    在婚 45.032 <0.001
     是 63 258(91.2) 33.8(33.2~34.4) 39.2(38.6~39.8 ) 27.0(26.3~27.6 )
     否 6 111(8.8) 30.3(28.2~32.4) 39.2(37.3~41.2 ) 30.5(28.4~32.6 )
    医疗保险 22.653 <0.001
     是 60 181(86.8) 33.7(33.0~34.3) 39.2(38.6~39.8) 27.1(26.4~27.8)
     否 9 188(13.2) 31.0(29.3~32.7) 39.4(37.8~41.0) 28.5(26.8~30.3)
    CVD史 134.228 <0.001
     是 3 412(4.9) 25.9(23.0~28.8) 39.4(36.8~42.0) 34.7(32.0~37.4)
     否 65 957(95.1) 33.9(33.3~34.5) 39.2(39.6~39.8) 26.9(26.3~27.6)
    吸烟 196.524 <0.001
     是 17 335(25.0) 37.8(36.6~39.0) 36.4(35.2~37.6) 25.8(24.5~27.1)
     否 52 034(75.0) 32.0(31.3~32.7) 40.2(39.5~40.8) 27.8(27.1~28.5)
    饮酒 33.767 <0.001
     是 18 740(27.0) 32.4(31.2~33.6) 38.9(37.8~40.0) 28.7(27.5~29.9)
     否 50 111(72.2) 33.9(33.2~34.6) 39.3(38.7~40.0) 26.7(26.0~27.5)
     不清楚 518(0.8) 29.5(22.3~36.8) 40.9(34.3~47.5) 29.5(22.3~36.8)
    合计 69 369(100.0) 33.5(32.9~34.1) 39.2(38.6~39.8) 27.3(26.7~27.9)
    标化率 35.2(35.1~35.3) 38.6(38.0~39.2) 26.0(25.4~26.6)
    注:a. 括号外数字表示患病率,括号内数据表示患病率的95%置信区间; CVD. 心血管疾病
    下载: 导出CSV

    表  2  内蒙古自治区35~75岁居民的心血管代谢性疾病和共病患病情况

    Table  2.   Prevalence of cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35 - 75 years in Inner Mongolia

    危险因素合计非中心型肥胖轻度中心型肥胖重度中心型肥胖χ2P
    高血压3 269.324<0.001
     是55.8(55.3~56.3)42.3(41.4~43.3)57.5(56.8~58.3)69.9(69.1~70.7)
     否44.2(43.6~44.7)57.7(56.8~58.5)42.5(41.5~43.4)30.1(28.9~31.3)
    糖尿病1 784.620<0.001
     是19.5(18.9~20.2)11.7(10.5~12.9)20.4(19.3~21.4)28.0(26.8~29.2)
     否80.5(80.1~80.8)88.3(87.9~88.8)79.6(79.1~80.1)72.0(71.3~72.8)
    血脂异常3 278.491<0.001
     是33.6(33.0~34.2)20.3(19.2~21.5)36.1(35.1~37.0)46.3(45.2~47.3)
     否66.4(66.0~66.8)79.7(79.1~80.3)63.9(63.2~64.6)53.7(52.7~54.7)
    共病4 637.161<0.001
     是30.8(30.2~31.4)15.9(14.7~17.1)32.6(31.6~33.5)46.5(45.4~47.5)
     否69.2(68.8~69.6)84.1(83.6~84.6)67.4(66.8~68.1)53.5(52.6~54.5)
    注:括号外数据表示患病率,括号内数据表示患病率的95%置信区间
    下载: 导出CSV
  • [1] Wang YF, Zhao L, Gao LW, et al. Health policy and public health implications of obesity in China[J]. Lancet Diabetes Endocrinol, 2021, 9(7): 446–461. DOI: 10.1016/S2213−8587(21)00118−2.
    [2] Pan XF, Wang LM, Pan A. Epidemiology and determinants of obesity in China[J]. Lancet Diabetes Endocrinol, 2021, 9(6): 373–392. DOI: 10.1016/S2213−8587(21)00045−0.
    [3] GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019[J]. Lancet, 2020, 396(10258): 1204–1222. DOI: 10.1016/S0140−6736(20)30925−9.
    [4] 金璐, 邵姜超, 刘文昊, 等. 烟台市成年居民肥胖流行现状及影响因素分析[J]. 中国卫生统计,2022,39(4):607–609. DOI:10.3969/j.issn.1002−3674.2022.04.031.

    Jin L, Shao JC, Liu WH, et al. Analysis of the prevalence and influencing factors of obesity among adult residents in Yantai[J]. Chin J Health Stat, 2022, 39(4): 607–609. DOI: 10.3969/j.issn.1002−3674.2022.04.031.
    [5] 吴超群, 李希, 路甲鹏, 等. 中国居民心血管疾病危险因素分布报告[J]. 中国循环杂志,2021,36(1):4–13. DOI:10.3969/j.issn.1000−3614.2021.01.002.

    Wu CQ, Li X, Lu JP, et al. Report on geographical disparity of cardiovascular risk factors in China[J]. Chin Circul J, 2021, 36(1): 4–13. DOI: 10.3969/j.issn.1000−3614.2021.01.002.
    [6] 王燕逍翔, 白建军, 宇传华. 基于全球视角的中国心血管病疾病负担现状及趋势[J]. 公共卫生与预防医学,2021,32(6):6–11. DOI:10.3969/j.issn.1006−2483.2021.06.002.

    Wang YXX, Bai JJ, Yu CH. Status and trend of cardiovascular disease burden in China from a global perspective[J]. J Pub Health Prev Med, 2021, 32(6): 6–11. DOI: 10.3969/j.issn.1006−2483.2021.06.002.
    [7] Xu XQ, Bao H, Tian ZX, et al. Prevalence, awareness, treatment, and control of hypertension in Northern China: a cross-sectional study[J]. BMC Cardiovasc Disord, 2021, 21(1): 525. DOI: 10.1186/s12872−021−02333−7.
    [8] 中国肥胖问题工作组. 中国成人超重和肥胖症预防与控制指南(节录)[J]. 营养学报,2004,26(1):1–4. DOI: 10.13325/j.cnki.acta.nutr.sin.2004.01.001.

    Chinese Working Group on Obesity. Guidelines for prevention and control of overweight and obesity in Chinese adults (excerpt)[J]. Acta Nutrim Sin, 2004, 26(1): 1–4. DOI:  10.13325/j.cnki.acta.nutr.sin.2004.01.001.
    [9] Zhang P, Wang R, Gao C S, et al. Types of obesity and its association with the clustering of cardiovascular disease risk factors in Jilin province of China[J]. Int J Environ Res Public Health, 2016, 13(7): 685. DOI:  10.3390/ijerph13070685.
    [10] 胡晶晶, 赵佳, 谢梦, 等. 上海市杨浦区居民中心型肥胖与心血管疾病危险因素及聚集性的关系[J]. 上海预防医学,2020,32(1):36–40. DOI: 10.19428/j.cnki.sjpm.2020.18979.

    Hu JJ, Zhao J, Xie M, et al. Relationship between central obesity and cardiovascular disease risk factors and resident aggregation in Yangpu district, Shanghai[J]. Shanghai J Prev Med, 2020, 32(1): 36–40. DOI:  10.19428/j.cnki.sjpm.2020.18979.
    [11] 尤莉莉, 乌云高娃, 吴和平, 等. 内蒙古某地区男性超重肥胖和饮酒对血尿酸的影响[J]. 中国慢性病预防与控制,2013,21(6):659–662. DOI:10.16386/j.cjpccd.issn.1004−6194.2013.06.027.

    You LL, Wuyun GW, Wu HP, et al. The effects of overweight, obesity and drinking on serum uric acid in male residents of Inner Mongolian[J]. Chin J Prev Contr Chron Dis, 2013, 21(6): 659–662. DOI: 10.16386/j.cjpccd.issn.1004−6194.2013.06.027.
    [12] He X, Liu C, Chen YL, et al. Overweight without central obesity, cardiovascular risk, and all-cause mortality[J]. Mayo Clin Proc, 2018, 93(6): 709–720. DOI:  10.1016/j.mayocp.2018.01.027.
    [13] Shirasawa T, Ochiai H, Yoshimoto T, et al. Associations between normal weight central obesity and cardiovascular disease risk factors in Japanese middle-aged adults: a cross-sectional study[J]. J Health Popul Nutr, 2019, 38(1): 46. DOI: 10.1186/s41043−019−0201−5.
    [14] Lecaire TJ, Klein BEK, Howard KP, et al. Risk for end-stage renal disease over 25 years in the population-based WESDR cohort[J]. Diabetes Care, 2014, 37(2): 381–388. DOI: 10.2337/dc13−1287.
    [15] 赵冬. 心血管疾病危险因素的研究: 过去、现在和未来[J]. 中国循环杂志,2021,36(1):1–3. DOI:10.3969/j.issn.1000−3614.2021.01.001.

    Zhao D. Research on risk factors of cardiovascular disease: past, present and future[J]. Chin Circul J, 2021, 36(1): 1–3. DOI: 10.3969/j.issn.1000−3614.2021.01.001.
    [16] 中国心血管病风险评估和管理指南编写联合委员会. 中国心血管病风险评估和管理指南[J]. 中华预防医学杂志,2019,53(1):13–35. DOI:10.3760/cma.j.issn.0253−9624.2019.01.004.

    The Joint Task Force for Guideline on the Assessment and Management of Cardiovascular Risk in China. Guideline on the assessment and management of cardiovascular risk in China[J]. Chin J Prev Med, 2019, 53(1): 13–35. DOI: 10.3760/cma.j.issn.0253−9624.2019.01.004.
  • 加载中
图(2) / 表(2)
计量
  • 文章访问数:  390
  • HTML全文浏览量:  236
  • PDF下载量:  26
  • 被引次数: 0
出版历程
  • 收稿日期:  2023-02-06
  • 网络出版日期:  2023-07-03

目录

    /

    返回文章
    返回

    在线交流

    防诈骗公告

    大家好:近期有不法分子以本刊编辑身份添加作者微信,请务必提高警惕!本刊关于稿件的一切事项通知均采用编辑部唯一邮箱(jbjc@icdc.cn)和座机(010-58900732)联系作者,且在录用稿件后仅收取版面费,无其他任何名目费用(如审稿费和加急费等),非编辑部邮箱发送的本刊收费用通知等均为诈骗,不要随意汇入款项!如有可疑及时致电编辑部核实确认!