肝癌患者庚型肝炎病毒感染血清学研究

A Seroepidemiological Study on HGV Infection in HCC Patients

摘要: 采用抗－ＨＧＶ酶联免疫试验（ＥＩＡ）对１６０例肝细胞癌（ＨＣＣ）和１３０人健康人群进行了检测，结果抗－ＨＧＶ阳性率分别为１４．３８％和２．３１％，表明在不同人群中存在庚型肝炎病毒（ＨＧＶ）感染；ＨＣＣ患者抗－ＨＧＶ阳性率明显高于健康人群，显示ＨＧＶ感染与ＨＣＣ发生有关；同时在抗－ＨＧＶ阳性ＨＣＣ患者中ＨＢＶ感染率高达８２．６１％，提示ＨＧＶ和ＨＢＶ重叠感染可增加ＨＣＣ的发生.

Abstract: The serum samples of 160 hepatocellular carcinoma (HCC) cases and 130 health people were detected with enzyme immunoassay (EIA),the results showed that the positive rate of antiHGV were 14.38% and 2.31% respectively.It indicated that there was infection of HGV among different groups of people,the positive rate of antiHGV in HCC patients was significaltly higher than that in health people.The authors postulated that the HGV infection maybe the cause of HCC.At the same time,the rate of HBV infection was 82.61% in the anti-HGV positive cased of HCC patients,which prompted that the overlapping infection of HGV and HBV increased the risk of HCC occurring.