Abstract: Objective To analysis and summarize the influenza epidemic tendency and the etiological characteristics on the basis of results made by the influenza-monitoring network in Guangzhou city in 2003. Methods Epidemiological surveillance, forms of influenza-like cases should be filled and filed weekly in monitoring point hospitals; individual cases of influenza-like disease should be surveyed and reported by CDC doctors at district and county level. Etiological surveillance, 5-10 portions of mouth rinsing liquid should be col-lected weekly from patients with influenza-like disease in monitoring point hospitals to do influenza virus sepa-ration. Serological monitoring,to monitor the antibody level of sera of common peoplie in March and Septem-ber;and to monitor the influenza sera of people vocationally exposed in poultry.Results 91 outbreak of in-fluenza epidemic were reported all the year,and the morbility rate was from 0.35% to 40%. For etiological monitoring,influenza A (H3N2)was found to be the predominant strain throughout year,and the influenza B only caused sporadic cases or small-scale outbreak.For serological surveillance,two results in March and September showed that,bef\ore and after the peak of influenza,positive rates of H1N1、H3N2、B (Victorian se-ries) sub types were identical (X2=0.82,2.01,1.34,P>0.05),but B (Panama series) antibody in Septent-ber was higher than that in March (X2=0.022,P1N1、H3N2、B were 42.97%、 88.21%、59.09%，respectively. The H5N1 test results of poultry were all negative. There were 5 positive H3N2 cases,and the positive rate was 1.89%.Conclusion High incidence of influenza occurred between spring and summer in 2003,and the H3N2 was the predominant epidemic strains in the whole year.