Abstract: ObjectiveTo evaluate the quality of disinfection in hospitals in Guangdong province, find out the problems in disinfection surveillance and strengthen the surveillance of nosocomial infections. MethodsSince the surveillances on the quality of disinfection in hospitals were conducted by the centers for diseases control and prevention in Guangdong Province according to the same guidelines from 2005 to 2007, the surveillance data were collected and analyzed by SPSS software. ResultsFrom 2005-2007, 142 969, 140 014 and 161 991 samples for surveillance were detected with the qualified rate of 91.10％, 90.71％ and 91.22％ respectively, the overall qualified rate was 91.02％. The differences on qualified rates in 3 years had no statistical significance by I/Isup2/sup test (I/Isup2/sup=1.644, IP/I＞0.05). The qualified rates of hospitals at municipal, county and township level in 3 years were 93.59％, 93.94% and 89.34％ respectively，which had statistical significance by I/Isup2/sup test. The qualified rates in all municipal and county hospital were higher than in township health centers. Among the surveillance items, the qualified rate of disinfectant was the highest (97.62％), followed by pressure steam sterilizing (95.98％) and sterilizing medical instruments (95.63％). The qualified rate for the hand disinfection of medical staff was 90.67％. The qualified rate of the bacterial contents in air was the lowest (73.25%) The difference on the qualified rate of different items had statistical significance. ConclusionThe disinfection surveillance in hospitals at different level should be differed on the field to be monitored, and the disinfection surveillance for medical agencies at township level is the priority in future.