一起学校肺炎支原体暴发疫情的流行特征

Epidemiologic characteristics of a Mycoplasma pneumonia outbreak in a primary school

摘要: 探讨一起学校肺炎支原体暴发疫情的流行传播特征。采集标本检测肺炎支原体核酸与抗体，应用现场流行病学调查方法分析疫情。该校共计发病21例，学校罹患率31.91%（15/47），家庭续发率33.33%（6/18），患者咽拭子标本肺炎支原体核酸阳性，患者肺炎支原体抗体为（41.506.93）ng/L，未发病者（35.111.41）ng/L，二者差异无统计学意义（t=2.03，P=0.48）。首例病例未采取隔离引起暴发，早期做好呼吸道隔离，预防交叉感染极其重要。

Abstract: To identify and describe the epidemiological characteristics of an outbreak of Mycoplasma pneumoniae(MP) infection in an school. Throat swabs and blood samples were collected from the patients. MP DNA and antibody(MP-Ab) were quantitatively determined. Twenty one MP infection cases were reported. The attack rate was 31.91% (15/47), and the family secondary attack rate was 33.33%(6/18). The throat swabs from the patients were positive for MP by PCR detection, the MP-Ab was 41.506.93 in the patients and 35.111.41 in the unaffected in the same class, showing no significant difference(t=2.03,P=0.48). MP infection was the main cause of this outbreak. The index case was not isolated promptly, which suggested that It is essential to take early isolation measure to prevent the spread of infection.