Abstract:
Objective To analyze the morbidity rate, mortality rate of colorectal cancer and survival rate of colorectal cancer in Yuyao registered residents from 2015 to 2021.
Methods The incidence and death data of colorectal cancer in Yuyao registered residents during 2015−2021 were collected to calculate the crude morbidity and mortality rates, the age-specific morbidity and mortality rates, 0−74 years cumulative rate and 35−64 years truncated rate. The standardized rate was calculated based on the Chinese population from the census in 2010 and Segi's standard world population. The gender differences of each group were compared by χ2 test. The annual percentage change (APC) and average annual percentage change (AAPC) were calculated by Joinpoint Regression Program 4.9.0.1, and the survival of the cases was analyzed by Kaplan-Meier method combined with Log-Rank test.
Results From 2015 to 2021, a total of 2 843 new cases of colorectal cancer occurred in Yuyao, ranking second in the cases of tumors, the average annual crude morbidity rate was 48.58/100 000, the age-standardized rate by Chinese standard population (ASRC) was 27.12/100 000, and the age-standardized rate by world Segi's population (ASRW) was 20.69/100 000, the cumulative rate of 0−74 years old was 2.48%, and the truncated rate of 35−64 years old was 31.94/100 000. The crude morbidity rate and the ASRC showed upward trends (APC was 7.36%, 4.00%, both P<0.01); A total of 1102 deaths of colorectal cancer occurred during this period, ranking the fifth in the deaths of tumors. The average annual crude mortality rate was 18.83/100 000, the ASRC was 9.87/100 000, and the ASRW was 7.09/100 000, the cumulative rate of 0−74 years old was 0.67%, and the truncated rate of 35−64 years old was 8.11/100 000. The changes of the crude mortality rate and ASRC were not obvious (APC was 3.71%, 0.19%, both P>0.05); All rates were higher in men than in women. The morbidity rate and mortality rate all increased with age (AAPC was 7.67%, 8.39%, both P<0.01). The median of survival time of colorectal cancer cases was 4.71 years, and the 5−year survival rate was 59.12%.
Conclusion The morbidity and mortality of colorectal cancer remained high in Yuyao. It is necessary to promote healthy lifestyle and carry out early diagnosis and treatment of colorectal cancer in key groups (men and those over 40 years old), in order to reduce the risk of incidence and death of colorectal cancer, and improve the survival of the patients.